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Comparison of Objective Taste Perception in Controlled and Uncontrolled Hypothyroid Patients and Healthy Individuals
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ُS Hajimaghsoodi    , M Mirali , A Ghanei , F Owlia |
| Department of Oral and Maxillofacial Medicine, School of Dentistry, Shahid Sadoughi University of Medical Sciences, Yazd, Iran, , dr.owlia@gmail.com |
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Abstract: (29 Views) |
Introduction: Taste perception is known to be influenced by alterations in thyroid function. Nevertheless, many hypothyroid patients—and their physicians—remain unaware of the presence of dysgeusia. This study aimed to provide deeper insight into taste perception among individuals with controlled and uncontrolled hypothyroidism compared with healthy controls. Materials and Methods: A total of 40 controlled hypothyroid patients, 40 uncontrolled hypothyroid patients, and 40 healthy controls were enrolled. Participants were assigned to groups based on biochemical confirmation of normal or abnormal thyroid function. Associations between detection thresholds for the four basic tastes and participants’ age, sex, and thyroid stimulating hormone (TSH) levels were assessed. Statistical analyses were conducted using the Kruskal–Wallis test, ANOVA, Chi-square test, and Spearman’s rank correlation. Results: No statistically significant differences in taste detection thresholds for the four basic tastes were found among the three groups. Similarly, TSH levels were not significantly correlated with taste thresholds for any of the tastes. A significant correlation was observed between age and sour taste threshold. Additionally, sour taste thresholds differed significantly between male and female participants. Conclusion: No evidence was found for influence of thyroid hormones on the taste perception thresholds of the four main tastes in the studied population. It is recommended that future research be conducted under more controlled conditions, including the use of more precise methods for assessing taste thresholds. |
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| Keywords: Taste perception, Taste sensitivity, Hypothyroidism, Dysgeusia, Sour taste |
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Full-Text [PDF 958 kb]
(13 Downloads)
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Type of Study: Original |
Subject:
Endocrinology
Received: 2025/11/21 | Accepted: 2026/02/9 | Published: 2026/04/30
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