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Longitudinal Association between MIND Diet Adherence and the Risk of Cardiometabolic Risk Factors: Tehran Lipid and Glucose Study
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M Golzarand    , M Javadi , P Mirmiran , F Azizi |
| Nutrition and Endocrine Research Center, Research Institute for Endocrine Disorders, Research Institute for Endocrine Sciences, Shahid Beheshti University of Medical Sciences, Tehran, Iran, , mahdieh_golzarand@yahoo.com |
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Abstract: (10 Views) |
Introduction: Numerous studies have demonstrated the beneficial effects of healthy plant-based diets in reducing and managing cardiometabolic risk factors. However, only a few cohort studies have investigated the link between adherence to the Mediterranean-DASH intervention for neurodegenerative delay diet (MIND) and cardiometabolic risk factors. Consequently, this study was designed to explore the relationship between adherence to the MIND diet and the incidence of cardiometabolic risk factors among Iranian adults. Materials and Methods: In this cohort study, we selected 3055 adults from the Tehran Lipid and Glucose Study (TLGS). A food frequency questionnaire was used to assess participants' dietary intake and determine their MIND diet score. Cardiometabolic risk factors included high waist circumference, hypertension, hypertriglyceridemia, low HDL, hyperglycemia, and metabolic syndrome. The association between the MIND diet and each cardiometabolic risk factor was analyzed using Cox proportional hazards regression, with results reported as hazard ratios and 95% confidence intervals. Results: The mean age of participants was 38.1 years, and 53.6% were women. The study lasted 8.0 years, and the mean (standard error) MIND diet score was 8.02 (1.14). The average intake of ultra-processed foods was four servings per day. After adjusting for all potential confounders, the hazard ratios (95% CI) for various conditions were as follows: metabolic syndrome, 0.82(0.77-0.88); hypertriglyceridemia, 0.81(0.75-0.88); low HDL, 0.80(0.72-0.90); hypertension, 0.78(0.73-0.83); hyperglycemia, 0.82(0.77-0.88); and high waist circumference, 0.82(0.76-0.88) per each 1-point increase in the MIND diet score. Conclusion: This study found an inverse association between adherence to the MIND diet and cardiometabolic risk factors. |
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| Keywords: MIND diet, Hypertriglyceridemia, Hypertension, Waist circumference, Cardiometabolic risk factors |
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Full-Text [PDF 927 kb]
(7 Downloads)
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Type of Study: Original |
Subject:
Nutrition
Received: 2025/06/9 | Accepted: 2025/10/19 | Published: 2025/03/30
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