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:: Volume 15, Issue 2 (8-2013) ::
2013, 15(2): 183-189 Back to browse issues page
The Effect of Resistance Training Intensity on Serum ApoA-I Concentration in Streptozotocin-Induced Diabetic Rats
Elahe Talebi-Garakani Dr , Alireza Safarzade Dr
Mazandaran University , Talebi_umz@yahoo.com
Abstract:   (6319 Views)

Introduction: Cardiovascular disease is the major cause of death in persons with type 1 diabetes. Although physical activity has been associated with a reduction in cardiovascular mortality in type 1 diabetes patients, there is limited information available regarding physical activity, resistance in particular, resistance training on the lipid profiles and apolipoprotein A-I (apoA-I) in these patients. The aim of this study was to investigate the effects of 4 weeks resistance training on serum lipid profiles and apoA-I levels in type 1 diabetic rats. Materials and Methods: Thirty-two male Wister rats (290 ± 20 g) were randomly divided into four groups: Healthy control (C), diabetic controls (DC), diabetic, trained with 50% body mass (DT1), and diabetic, trained with 100% body mass (DT2). Resistance training consisted of climbing a ladder carrying a load suspended from the tail. After 4 weeks of resistance training, serum lipid profiles, glucose and apoA-I concentr­ations were measured. Results: At the end of study, we found no significant differences in serum lipid profiles and glucose concentrations between the diabetic groups. In the DT2 group, serum apoA-I levels significantly increased, compared with the C and DC groups (P<0.001 and P= 0.023, respectively). Conclusion: Serum apoA-I concentrations, in streptozotocin induced diabetic rats, are increased by resistance training, the alterations being affected by its intensity, without any significant changes in their lipid profiles.

 

Keywords: Apolipoprotein A-I, Intensity of training, Diabetes mellitus, Lipid profile, Rats
Full-Text [PDF 290 kb]   (1733 Downloads)    
Type of Study: Original | Subject: Exercise
Received: 2012/07/30 | Accepted: 2013/07/29 | Published: 2013/07/29
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Talebi-Garakani E, safarzade A. The Effect of Resistance Training Intensity on Serum ApoA-I Concentration in Streptozotocin-Induced Diabetic Rats. Iranian Journal of Endocrinology and Metabolism. 2013; 15 (2) :183-189
URL: http://ijem.sbmu.ac.ir/article-1-1425-en.html


Volume 15, Issue 2 (8-2013) Back to browse issues page
مجله ی غدد درون‌ریز و متابولیسم ایران، دو ماهنامه  پژوهشی مرکز تحقیقات غدد درون‌ریز و متابولیسم، Iranian Journal of Endocrinology and Metabolism
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