[Home ] [Archive]   [ فارسی ]  
:: Main :: About :: Current Issue :: Archive :: Search :: Contact ::
Main Menu
Home::
Journal Information::
Articles archive::
For Authors::
For Reviewers::
Subscription::
Contact us::
Site Facilities::
::
Search in website

Advanced Search
Receive site information
Enter your Email in the following box to receive the site news and information.
Last site contents
:: Editorial Board
:: About Iranian Journal of Endocrinology and Metabolism
:: Volume 7, Issue 4 (12-2005) ::
2005, 7(4): 365-373 Back to browse issues page
Evaluation of HDL-C determination methods
M Hedayati , MS Daneshpour
, hedayati@erc.ac.ir
Abstract:   (25684 Views)
Following confirmation of the role of HDL-C role in cardiovascular disease, its measurement has become a fixed requirement by physicians. Today serum HDL-C is measured using different methods from simple outdated precipitation methods to the latest of homogenous assays used for HDL-C determination. However, the precision, accuracy and performance, standardization, and evaluation for those methods are controversial. This paper briefly discusses the methodology of various HDL-C determination methods e.g ultra centrifugation, electrophoresis, precipitation and homogenous assays, and advantages of homogenous methods. Human expertise, time consuming and high cost instrumentation of ultra centrifugation, quantitative electrophoresis, nuclear magnetic resonance and chromatographic methods are key factors that make the methods undesirable for clinical laboratories. Precipitation and manual separation steps of non homogenous HDL-C determination methods, reduces their precision, and causes them to be replaced by more precise methods such as homogenous assays however more time is needed for their costs to be more competitive.
Keywords: Evaluation, HDL-C, Determination.
Full-Text [PDF 332 kb]   (5047 Downloads)    
Type of Study: Original | Subject: Endocrinology
Received: 2006/11/15 | Published: 2005/12/15
Add your comments about this article
Your username or Email:

CAPTCHA


XML   Persian Abstract   Print


Download citation:
BibTeX | RIS | EndNote | Medlars | ProCite | Reference Manager | RefWorks
Send citation to:

Hedayati M, Daneshpour M. Evaluation of HDL-C determination methods. Iranian Journal of Endocrinology and Metabolism 2005; 7 (4) :365-373
URL: http://ijem.sbmu.ac.ir/article-1-93-en.html


Rights and permissions
Creative Commons License This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.
Volume 7, Issue 4 (12-2005) Back to browse issues page
مجله ی غدد درون‌ریز و متابولیسم ایران، دو ماهنامه  پژوهشی مرکز تحقیقات غدد درون‌ریز و متابولیسم، Iranian Journal of Endocrinology and Metabolism
Persian site map - English site map - Created in 0.05 seconds with 36 queries by YEKTAWEB 4691