[Home ] [Archive]   [ فارسی ]  
:: Main :: About :: Current Issue :: Archive :: Search :: Contact ::
:: Volume 11, Issue 2 (3-2010) ::
2010, 11(2): 169-175 Back to browse issues page
Comparison of Adiponectin and Leptin Levels in Obese Children and Adolescents
MR Hamedinia , MA Sardar, AH Haghighi, J Porjahed
, mrhamedinia@sttu.ac.ir
Abstract:   (36211 Views)
Abstract Introduction: Leptin, a protein with a cytokine-like helical structure and molecular weight of 16 KDa, regulates the body weight and homeostasis of the energy in the body. Adiponectin has protective and special metabolic effects as well as anti-inflammatory ones, and the adiponectin level in human blood has an inverse ratio relation with the insulin resistance. The purpose of this study was to compare levels of leptin and adiponectin, and related hormones in the serum of obese children and adolescents. Materials and Methods: Sixty obese subjects were divided into two groups of 30 children and 30 adolescents. Anthropometric characteristics were recorded and adiponectin and leptin testosterone, growth, insulin, and cortisol hormones were measured in a fasting state in all subjects. Results: The serum levels of leptin (101%), adiponectin (98%) and cortisol hormone (38.62%) were significantly higher in children than in adolescents (p<0/05). When leptin and adiponectin were adjusted to body fat mass, the same results were observed. Serum levels of testosterone (82.58%), insulin (34.47%) and growth hormone (36.36%) were significantly higher in adolescents than in children (p<0/05). The ratio of leptin to adiponectin had no significant difference among children and adolescents. Conclusion: Levels of leptin and adiponectin are higher in children than in adolescents.
Keywords: Adiponectin, Leptin, Obesity, Children, Adolescents, Insulin
Full-Text [PDF 282 kb]   (2914 Downloads)    
Type of Study: Original |
Received: 2009/08/19
Add your comments about this article
Your username or Email:

CAPTCHA


XML   Persian Abstract   Print


Download citation:
BibTeX | RIS | EndNote | Medlars | ProCite | Reference Manager | RefWorks
Send citation to:

Hamedinia M, Sardar M, Haghighi A, Porjahed J. Comparison of Adiponectin and Leptin Levels in Obese Children and Adolescents. Iranian Journal of Endocrinology and Metabolism. 2010; 11 (2) :169-175
URL: http://ijem.sbmu.ac.ir/article-1-762-en.html


Volume 11, Issue 2 (3-2010) Back to browse issues page
مجله ی غدد درون‌ریز و متابولیسم ایران، دو ماهنامه  پژوهشی مرکز تحقیقات غدد درون‌ریز و متابولیسم، Iranian Journal of Endocrinology and Metabolism
Persian site map - English site map - Created in 0.06 seconds with 32 queries by YEKTAWEB 3991