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:: Volume 9, Issue 1 (Junne 2007 2007) ::
2007, 9(1): 11-18 Back to browse issues page
Changes in body weight and body fat distribution as risk factors for metabolic syndrome in Iranian women
A Saeedpour, P Mirmiran PhD, M Padyab, F Azizi
, azizi@erc.ac.ir
Abstract:   (31146 Views)
Introduction:To examine the association between changes in body weight and body fat distribution and development of metabolic syndrome. Materials and Methods: Changes in body weight and body fat distribution and the appearance of metabolic syndrome over a 3 year duration were assessed in 2176 women of the Tehran Lipid and Glucose Study. Metabolic syndrome was defined according to ATPIII criteria. Body fat distribution was determined by waist to hip ratio, waist circumference and hip girth. Stable waist and hip were defined successively as±2cm and -2cm to 0cm, respectively. Results: The mean age of subjects was 36.4±12.7 years and the incidence of metabolic syndrome was 19 percent during this period. After controlling for age, family history, smoking status and physical activity, weight gain was monotonically related to the risk of development of metabolic syndrome (for each Kg of weight gained, risk increased by 1.15%). Changes in waist to hip ratio of over 0.07 cm, were significantly associated with risk (P<0.05), independent of the risk associated with weight change. Compared with women who had a stable waist, ≥ 3cm increase in waist circumference had 3.33 times (95%CI: 2.14-5.22) the risk of metabolic syndrome and ≥ 5cm increase in hip girth had 1.58 times (95%CI: 0.99-2.54) the risk of metabolic syndrome. Conclusion: Findings show that changes in weight and body fat distribution are associated with the risk of metabolic syndrome.
Keywords: Metabolic syndrome, Body fat distribution, Weight change, Body fat distribution
Full-Text [PDF 368 kb]   (2254 Downloads)    
Type of Study: Original | Subject: Endocrinology
Received: 2007/08/20
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Saeedpour A, Mirmiran P, Padyab M, Azizi F. Changes in body weight and body fat distribution as risk factors for metabolic syndrome in Iranian women. Iranian Journal of Endocrinology and Metabolism. 2007; 9 (1) :11-18
URL: http://ijem.sbmu.ac.ir/article-1-371-en.html


Volume 9, Issue 1 (Junne 2007 2007) Back to browse issues page
مجله ی غدد درون‌ریز و متابولیسم ایران، دو ماهنامه  پژوهشی مرکز تحقیقات غدد درون‌ریز و متابولیسم، Iranian Journal of Endocrinology and Metabolism
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