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Determining the Frequency of Non-alcoholic Fatty Liver Disease in Patients with Type 2 Diabetes Mellitus and Some Related Factors
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M Zakerkish    , H Radkiyan , H Rashidi , SS Seyedian |
| Diabetes Research Center, Health Research Institute, School of Medicine, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran. , mehrnooshzakerkish@gmail.com |
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Abstract: (375 Views) |
Introduction: Non-alcoholic fatty liver disease (NAFLD) is currently the most frequent chronic liver disease affecting individuals of all age groups and is associated with type 2 diabetes mellitus (T2DM). The present study aimed to determine the frequency of NAFLD in adult patients with T2DM and some associated risk factors. Materials and Method: This descriptive cross-sectional study was conducted on patients diagnosed with T2DM at Golestan Hospital in Ahvaz, Iran, in 2020. All participants underwent abdominal ultrasonography to diagnose NAFLD and measure its grade. All the relevant clinical and biochemical characteristics were measured. Results: A total of 186 diabetic patients, including 75 women (40.32%) and 111 men (59.68%), with a mean age of 46.85±10.50 years, participated in this study. Ultrasound results revealed that all patients with T2DM (100%) had NAFLD, with 51 (27.42%) having fatty liver grade 1, 105 (56.45%) having grade 2, and 30 (16.13%) having grade 3. The severity of fatty liver in ultrasonography was directly and significantly correlated with smoking (P<0.001), weight (P<0.001), body mass index (BMI) (P<0.001), glycemic control (P=0.032), and high-density lipoprotein-cholesterol (HDL-C) level (P=0.001). Conclusion: Our results indicated that NAFLD was highly prevalent among patients with T2DM in our study population, and all patients exhibited varying grades of NAFLD. This finding demonstrates the importance of screening T2DM patients for NAFLD and the management of related risk factors in routine clinical settings. |
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| Keywords: Type-2 diabetes mellitus, Non-alcoholic fatty liver disease, Ultrasound |
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Full-Text [PDF 819 kb]
(244 Downloads)
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Type of Study: Original |
Subject:
Endocrinology
Received: 2023/09/3 | Accepted: 2024/04/14 | Published: 2023/09/1
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