[Home ] [Archive]   [ فارسی ]  
:: Main :: About :: Current Issue :: Archive :: Search :: Contact ::
Main Menu
Home::
Journal Information::
Articles archive::
For Authors::
For Reviewers::
Subscription::
Contact us::
Site Facilities::
::
Search in website

Advanced Search
Receive site information
Enter your Email in the following box to receive the site news and information.
Last site contents
:: Editorial Board
:: About Iranian Journal of Endocrinology and Metabolism
:: Volume 23, Issue 4 (11-2021) ::
2021, 23(4): 259-273 Back to browse issues page
Reciprocal Association between Thyroid Function and Metabolic Syndrome: A Review Article
L Mehran , S Mahdavi , A Amouzegar , F Azizi
Endocrine Research Center, Research Institute for Endocrine Sciences, Shahid Beheshti University of Medical Sciences, Tehran, Iran, , Amouzegar@endocrine.ac.ir
Abstract:   (1255 Views)
Introduction: Thyroid dysfunction can impair fat and glucose metabolism, blood pressure, and body weight. On the other hand, metabolic syndrome (MetS) can be associated with an increased risk of hypothyroidism. Due to the high prevalence of both disorders and the possibility of synergistic metabolic detrimental consequences in combination, this review study aimed to investigate the reciprocal association between thyroid function and MetS. Materials and Methods: Articles in PubMed and Web of Science written in English were searched from 1991 to 2021 using search terms hypothyroidism, hyperthyroidism, thyroid hormones, thyroxine, thyroid-stimulating hormone, and metabolic syndrome in titles and abstracts. Results: Hypothyroidism and even changes in thyroid hormones within the normal range are associated with disorders of various metabolic risk factors; however, the risk of developing MetS in people with both euthyroidism and subclinical hypothyroidism remains a controversial issue. Hyperthyroidism may be associated only with insulin resistance and impaired blood sugar levels (dysglycemia). Although the effect of various metabolic disorders such as obesity and diabetes on thyroid function has been observed, the results are contradictory regarding the prevalence and incidence of thyroid dysfunction in patients with MetS and healthy individuals. Conclusion: The association between MetS, thyroid function, and thyroid hormones is reciprocal and complex and may be affected by age, gender, insulin resistance, smoking, iodine intake, and inflammatory markers.
Keywords: Free thyroxine, Metabolic Syndrome, Thyroid Hormones, Thyroid Stimulating Hormone, Hypothyroidism, Hyperthyroidism, Subclinical Hypothyroidism, Subclinical Hyperthyroidism
Full-Text [PDF 1087 kb]   (617 Downloads)    
Type of Study: Review | Subject: Endocrinology
Received: 2021/09/22 | Accepted: 2021/12/29 | Published: 2021/11/1
Add your comments about this article
Your username or Email:

CAPTCHA


XML   Persian Abstract   Print


Download citation:
BibTeX | RIS | EndNote | Medlars | ProCite | Reference Manager | RefWorks
Send citation to:

Mehran L, Mahdavi S, Amouzegar A, Azizi F. Reciprocal Association between Thyroid Function and Metabolic Syndrome: A Review Article. Iranian Journal of Endocrinology and Metabolism 2021; 23 (4) :259-273
URL: http://ijem.sbmu.ac.ir/article-1-2906-en.html


Rights and permissions
Creative Commons License This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.
Volume 23, Issue 4 (11-2021) Back to browse issues page
مجله ی غدد درون‌ریز و متابولیسم ایران، دو ماهنامه  پژوهشی مرکز تحقیقات غدد درون‌ریز و متابولیسم، Iranian Journal of Endocrinology and Metabolism
Persian site map - English site map - Created in 0.05 seconds with 38 queries by YEKTAWEB 4652