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Evaluation of 25-hydroxycholecalciferol and parathyroid hormone in Iranian patients with thyroid dysfunction
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AA MirSaeid Ghazi   |
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Abstract: (24805 Views) |
| Abstract: Due to high prevalence of bone manifestations in hyperthyroidism and in order to evaluate the contributing role of vitamin D stores in the pathogenesis of the disorder, serum 25-hydroxyvitamin D3 (25-OH-D) and parathormone (PTH) levels were evaluated in 33 hyperthyroid, 17 hypothyroid and 186 normal subjects from Tehran. Mean 25-OH-D levels in hyperthyroid patients (18.3±8.1 ng/ml) were not significantly different from normal subjects (20.±11.4). Mean levels of PTH in hyperthyroid group was not significantly different from normal subjects. In hypothyroid group mean PTH (45±17.9) was significantly higher than hyperthyroid patients (31.6±14) and normal controls (31.3±12.7) (P<0.003). There were no significant correlations between thyroid hormone levels and duration of the disorder with 25-OH-D and PTH levels. It seems that bone manifestations of hyperthyroidism are not solely attributed to vitamin D levels even in areas with moderate to severe vitamin D deficiency. |
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| Keywords: 25- Hydroxyvitamin D, Hyperthyroidism, Vitamin D |
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Type of Study: Original |
Subject:
Endocrinology
Received: 2006/11/30 | Published: 2000/12/15
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