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A study of the relationship between blood and saliva glucose levels in healthy population to find a non-invasive method for blood glucose measurement
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M Hashemipour   , F Nekuii , M Amini , A Aminalroaya , H Rezvanian , A Kachoii , AR Abdoli |
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Abstract: (35580 Views) |
| Abstract: Diabetic patients need to monitor blood glucose level (BGL) for diagnosis, treatment and follow up of their disease. Typically a blood sample for analysis is obtained via intravenous or a finger stick or other such invasive procedures. Often, this blood collecting causes physical and mental stress to the patient. For this reason, it is desirable to use other biologic liquids such as saliva to detect the blood glucose level. This article studies correlation coefficient between blood glucose level and salive glucose level (SGL) in healthy men. This is a descriptive, cross sectional study. 130 Blood and 130 saliva samples were obtained from 10 healthy men in 13 times in 5 days. Each day samples were taken in 3 times, fasting, postprandial and evening. Samples were analyzed with glucose oxidase method. Value of blood glucose level ranged from 58mg/dl to 118 mg/dl. Mean of fasting blood glucose level was 84.9±3.13mg/dl. Value of salive glucose level ranged from 0.322mg/dl to 4.941 mg/dl. Mean of saliva glucose level was 1.22±0.81mg/dl. Correlation coefficient between BGC and SGL from the 5 days of measurement was 0.23. Correlation coefficient for each day was 0.38 (first day), 0.21 (second day), 0.01 (third day) 0.37 (fourth day). Correlation coefficient for each person was 0.31 (case A). (case B), 0.07 (case C), 0.07 (case D), 0.45 (case E), 0.10 (case F), -0.05 (case E), 0.32 (case H), 0.87 (case I), 0.87 (case J). Unfortunately considering the values of correlation coefficients and the limited range of SGL we cannot use saliva for detecting BGL. |
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| Keywords: Diagnostic method, diabetes mellitus, blood sugar, saliva |
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Type of Study: Original |
Subject:
Endocrinology
Received: 2006/11/30 | Published: 2000/12/15
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