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:: Editorial Board
:: About Iranian Journal of Endocrinology and Metabolism
:: Volume 6, Issue 2 (6-2004) ::
2004, 6(2): 101-106 Back to browse issues page
A comparison between fine needle aspiration and non-aspiration in evaluating thyroid nodules
B Hadadi-Nejad , B Larijani , SM Tavangar , M Nooraie
Abstract:   (24020 Views)
Introduction: Thyroid nodules are important because of the risk of malignancy. Fine needle aspiration (FNA), the first diagnostic method in assessment of cytology of thyroid nodules, is a simple, available and cost-effective technique. The aim of this study was to compare the quality of cytomorphology sample, number of cells, the quality of architecture of thyroid papillae and follicles in FNA and fine needle non-aspiration (FNNA) techniques. Material and Methods: 200 patients of Shariati hospital, with palpable thyroid nodules, 1 to 4 cm in size, were recruited. FNA and FNNA techniques were applied to each patient. In a single-blind setting, all specimens were examined by the same cytopathologist. The specimens were scored (0, 1 or 2) on the basis of background blood or clot, number of obtained cells, preserved architecture of papillae and follicles and cellular degeneration. Nonparametric methods were used to compare scores of the two techniques. Results: 200 patients (162 female, 38 male) were entered the study. Specimens from 43 patients were inadequate. In the remaining 157 patients there was no statistically significant difference between average scores in the quality of cytomorphology sample, number of cells, quality of architecture of thyroid papillae and follicles and cellular degeneration in FNNA and FNA. Conclusion: It seems that FNNA is not superior to FNA in the cytopathologic studies of thyroid nodules and there is an agreement between two methods.
Keywords: Fine needle aspiration, Fine needle non-aspiration, Thyroid nodules, Cytology
Full-Text [PDF 268 kb]   (3044 Downloads)    
Type of Study: Original | Subject: Endocrinology
Received: 2006/11/23 | Published: 2004/06/15
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Hadadi-Nejad B, Larijani B, Tavangar S, Nooraie M. A comparison between fine needle aspiration and non-aspiration in evaluating thyroid nodules. Iranian Journal of Endocrinology and Metabolism 2004; 6 (2) :101-106
URL: http://ijem.sbmu.ac.ir/article-1-229-en.html


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Creative Commons License This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.
Volume 6, Issue 2 (6-2004) Back to browse issues page
مجله ی غدد درون‌ریز و متابولیسم ایران، دو ماهنامه  پژوهشی مرکز تحقیقات غدد درون‌ریز و متابولیسم، Iranian Journal of Endocrinology and Metabolism
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