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:: Volume 4, Issue 3 (9-2002) ::
2002, 4(3): 195-199 Back to browse issues page
A case with androgenic granulosa cell tumor of the ovary
AA MirSaid Ghazi , H Delshad, R Mashayakhi, B Gafari
, ghazi@erc-iran-com
Abstract:   (26016 Views)
This article reports the cliniopathologic findings of an unusual case of granulosa cell tumor with androgenic manifestations in a 16-year-old girl. The patient presented with a 2-year history of amenorrhea. Physical examination revealed an increase in facial, chest and abdominal hair with breast atrophy and horseness of voice. Pelvic ultrasound demonstrated a 87x85x66mm left adnexal cyst. Plasma testosterone and 17-hydroxy progesterone levels were elevated. She underwent an exploratory laparotomy in which a left ovarian tumor, 8cm in diameter was found and extracted. Microscopic examination of the tumor revealed the typical features of a granulosa cell tumor of the ovary. Two months after surgery, plasma testosterone and 17-hydroxy progesterone levels were within the normal range and the patient had a regular menstrual cycle. To our knowledge, this represents the first case of a granulosa cell tumor with androgenic manifestations reported in Iranian literature.
Keywords: Granulosa cell tumor, Androgens, Testosterone, Ovarian neoplasm
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Type of Study: Case report | Subject: Endocrinology
Received: 2006/11/22
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MirSaid Ghazi A, Delshad H, Mashayakhi R, Gafari B. A case with androgenic granulosa cell tumor of the ovary. Iranian Journal of Endocrinology and Metabolism. 2002; 4 (3) :195-199
URL: http://ijem.sbmu.ac.ir/article-1-203-en.html


Volume 4, Issue 3 (9-2002) Back to browse issues page
مجله ی غدد درون‌ریز و متابولیسم ایران، دو ماهنامه  پژوهشی مرکز تحقیقات غدد درون‌ریز و متابولیسم، Iranian Journal of Endocrinology and Metabolism
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