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A case with androgenic granulosa cell tumor of the ovary
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AA MirSaid Ghazi   , H Delshad , R Mashayakhi , B Gafari |
| , ghazi@erc-iran-com |
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Abstract: (29747 Views) |
| This article reports the cliniopathologic findings of an unusual case of granulosa cell tumor with androgenic manifestations in a 16-year-old girl. The patient presented with a 2-year history of amenorrhea. Physical examination revealed an increase in facial, chest and abdominal hair with breast atrophy and horseness of voice. Pelvic ultrasound demonstrated a 87x85x66mm left adnexal cyst. Plasma testosterone and 17-hydroxy progesterone levels were elevated. She underwent an exploratory laparotomy in which a left ovarian tumor, 8cm in diameter was found and extracted. Microscopic examination of the tumor revealed the typical features of a granulosa cell tumor of the ovary. Two months after surgery, plasma testosterone and 17-hydroxy progesterone levels were within the normal range and the patient had a regular menstrual cycle. To our knowledge, this represents the first case of a granulosa cell tumor with androgenic manifestations reported in Iranian literature. |
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| Keywords: Granulosa cell tumor, Androgens, Testosterone, Ovarian neoplasm |
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Full-Text [PDF 0 kb]
(3141 Downloads)
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Type of Study: Case report |
Subject:
Endocrinology
Received: 2006/11/22 | Published: 2002/09/15
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