Comparing the Effects of High Intensity Endurance Training and Resistance Training on Irisin Levels and Insulin Resistance in Rats
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Rahman Soori , Ali asghar Ravasi , Saeed Hazrati molaee  |
Tehran University , soorirahman@yahoo.com |
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Abstract: (9354 Views) |
Introduction: Irisin is a myokine
released from a membrane protein FNDC5 and has positive effects on metabolism.
The aim of this study was to compare the effect of high intensity endurance
training (HIET) and resistance training (RT) on serum irisin and the insulin
resistance index in male rats. Materials and Methods: Twenty-four male
rats were randomly divided into the high intensity endurance training (HIET),
resistance training (RT) and control groups HIET was conducted on a treadmill
for 10 weeks, while RT consisted of climbing a ladder carrying a load suspended
from the tail. After 10 weeks of training, serum concentration of irisin,
glucose and insulin were measured. Results: Irisin serum levels
increased significantly following 10 weeks of HIET, compared with RT (P=0.008).
Glucose levels (P=0.001) and insulin resistance index (P=0.009) in the HIET
group were significantly lower than the RT group and the control group as well
(P=0.001). In addition, high intensity endurance training decreased the body
weight of the HIET group significantly (P=0.008). Also, Irisin was found to
have a significant negative correlation with glucose and insulin resistance
index, whereas no significant relationship was seen between irisin and insulin.
Conclusion: Compared to resistance training, HIET is more effective in
increasing irisin and the decreasing glucose and the insulin resistance index. |
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Keywords: High Intensity Endurance Training, Resistance Training, Irisin, Insulin Resistance, Rat |
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Full-Text [PDF 283 kb]
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Type of Study: Original |
Subject:
Exercise Received: 2015/01/24 | Accepted: 2015/06/1 | Published: 2015/09/16
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