[Home ] [Archive]   [ فارسی ]  
:: Main :: About :: Current Issue :: Archive :: Search :: Contact ::
:: Volume 17, Number 1 (6-2015) ::
2015, 17(1): 63-87 Back to browse issues page
Role of Probiotics in Glycemic Controls and Body Weight in Type 2 Diabetes: A Systematic of Human and Animal Studies
Elham Razmpoosh, Hanieh S Ejtahed, Dr. Parvin Mirmiran, Dr. Maryam Javadi *
Assistant Professor Qazvin University of Medical Sciences, Faculty of Health , mjavadi@qums.ac.ir
Abstract:   (3991 Views)

Introduction: Publications evaluating the effects of probiotics on glycemic parameters, body weight change and food intakes have increased steadily in recent years. This study hence assessed all related human and animal studies. Materials and Methods: In the present systematic review, we used search engines to collect relevant data until May 2014, concerning the effects of probiotics on body weight changes, fasting plasma glucose (FPG), oral glucose tolerance test (OGTT), glycated hemoglobin (HbA1c), insulin, and insulin resistance in T2DM. Results: Twenty-five animal and four human articles met our inclusion criteria, articles which generally reported positive effects of probiotics on glycemic parameters. Lactobacillus sub-strains were used in all studies except for one. Most of the human and animal studies reported significant reduction in FPG and delay in the onset of T2DM, respectively only animal studies reported significant reduction in OGTT. Few studies showed significant reduction and increase in HbA1c and insulin levels, respectively. Most studies reported significant increment in body weight after intervention, whereas only a few reported significant reductions in this parameter. Conclusion: This study showed that the administration of probiotics have beneficial effects on glycemic parameters, although their effects on body weight were inconsistent. Therefore, considering the controversial results among human and animal reports, more data evidence is needed to conduct a meta-analysis.

Keywords: Type 2 diabetes mellitus, Non dependent insulin diabetes mellitus, Body weight changes, Insulin levels, Glicated hemoglobin
Full-Text [PDF 541 kb]   (1177 Downloads)    
Type of Study: Review | Subject: Nutrition
Received: 2014/09/30 | Accepted: 2015/01/27 | Published: 2015/05/26
Add your comments about this article
Your username or email:

Write the security code in the box >



XML   Persian Abstract   Print


Download citation:
BibTeX | RIS | EndNote | Medlars | ProCite | Reference Manager | RefWorks
Send citation to:

Razmpoosh E, Ejtahed H S, Mirmiran P, Javadi M. Role of Probiotics in Glycemic Controls and Body Weight in Type 2 Diabetes: A Systematic of Human and Animal Studies. Iranian Journal of Endocrinology and Metabolism. 2015; 17 (1) :63-87
URL: http://ijem.sbmu.ac.ir/article-1-1806-en.html
Volume 17, Number 1 (6-2015) Back to browse issues page
مجله ی غدد درون‌ریز و متابولیسم ایران، دو ماهنامه  پژوهشی مرکز تحقیقات غدد درون‌ریز و متابولیسم، Iranian Journal of Endocrinology and Metabolism
Persian site map - English site map - Created in 0.051 seconds with 806 queries by yektaweb 3506