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:: Volume 16, Issue 2 (7-2014) ::
2014, 16(2): 111-118 Back to browse issues page
Effect of Twelve Weeks of Aerobic Training on Serum Levels of Leptin, Vaspin and Some Indicators of Oxidative Stress in Obese Middle-Aged Women
Mahmdou Hejazi , Zeynab Nezamdoost, Marziyeh Saghebjoo Dr
Azad University of Mashhad , nezamdoost2004@yahoo.com
Abstract:   (6529 Views)

Introduction: This study was conducted to determine the effect of twelve weeks of aerobic training on serum levels of leptin, vaspin, total antioxidant capacity (TAC) and malondialdehyde (MDA) in obese middle-aged women. Materials and Methods: In this quasi-experimental study, 30 sedentary, middle-aged women (mean±SD age 48.30±3.02 yr, body mass index 30.89±3.23 kg/m2 and body fat 32.88 ±2.71%) were randomized into the experimental (n=15) and control (n=15) groups. The experimental group performed twelve weeks aerobic training (3 times per week at an intensity of 65-75 % of maximum heart rate reserve). Blood samples were collected 24h before and 48h after the training. Data was analyzed by Student's t-test (P< 0.05). Results: Results showed a significant decrease in serum levels of leptin and MDA (P values 0.009 and 0.01 respectively) while TAC significantly increased (P=0.01) in the experimental group. Body fat percentage significantly decreased in the experimental group (0.0001), but serum vaspin levels were not significantly different between the two groups (P=0.93). Conclusions: Regular aerobic training is associated with weight loss and reduced body fat in obese women. As leptin production occurs in adipose tissue, subsequent decrease in body fat percent, serum leptin levels also occurred. On the other hand, aerobic training can improve oxidation/anti-oxidation in the body by reducing MDA concentration and increasing TAC.


Keywords: Aerobic exercise, Leptin, Vaspin, Malondialdehyde, Total antioxidant capacity, Middle-aged women
Full-Text [PDF 313 kb]   (2581 Downloads)    
Type of Study: Original | Subject: Physiology
Received: 2013/12/28 | Accepted: 2014/04/20 | Published: 2014/07/12
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hejazi M, nezamdoost Z, Saghebjoo M. Effect of Twelve Weeks of Aerobic Training on Serum Levels of Leptin, Vaspin and Some Indicators of Oxidative Stress in Obese Middle-Aged Women. Iranian Journal of Endocrinology and Metabolism. 2014; 16 (2) :111-118
URL: http://ijem.sbmu.ac.ir/article-1-1664-en.html

Volume 16, Issue 2 (7-2014) Back to browse issues page
مجله ی غدد درون‌ریز و متابولیسم ایران، دو ماهنامه  پژوهشی مرکز تحقیقات غدد درون‌ریز و متابولیسم، Iranian Journal of Endocrinology and Metabolism
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