Introduction: Physical activities can lead to the release of free radicals through oxidation pressure, and can also result in the decrease of free radicals in the body by producing anti-oxidation enzymes. However the key question is which type of exercise? The aim of this study was to analyze the effects of two kinds of physical activities, Eccentric and Concentric on some oxidation and anti-oxidation factors in the plasma of women involved in physical education. Materials and Methods: Twenty-four female student volunteers were randomly divided into 3 groups, the control group, the eccentric exercise group, and the concentric exercise group. Blood samples were taken from the test group twice (an hour before and again one hour after the training) in order to analyze the non-enzyme oxidation (GSH), oxidation pressure index (MDA) and absolute anti-oxidation capacity (ATC). Data was analysed using SPSS, version 13, through the analysis of variance test with 95% confidence (p<0.05). Result: Results showed that the amount of TAC, MDA, and GSH plasma after eccentric and concentric physical activities showed meaningful increases compared to before the activities. Also the amounts of GSH, MDA plasma after the eccentric and concentric activities had significant increase in comparison to the control group. Conclusion: It seems that severe eccentric and concentric physical activities are important stimulants causing considerable changes in the body’s oxidation system and these activities can improve anti-oxidation capacity.