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Related Factors of Acute Leukemia in Children and the Role of Breast Feeding
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Abstract: (10624 Views) |
| Introduction: In this study we aimed to determine factors related to the etiology of cancer in children. Materials and Methods: We investigated this issue in a case control study of 300 patients, aged 2±14 years, with acute leukemia, and 300 controls, individually matched to cases for age and sex, and place of residence. Children were enrolled after selection by a continuous sampling method. Information regarding breast-feeding was obtained through face to face interviews with mothers. Results: Breastfeeding for durations less than one month increased the risk for childhood acute leukemia. Also, results showed that children 18-13 months and 24-19 months were breast fed, respectively, 2.45 and 3.54 times less than had been breastfed children under 1 year were diagnosed with acute leukemia. (P<0.05). Higher number of children (OR=1.42, CI 1.03-1.96) and low family income (OR=0.6, CI 0.38-1.01) increased the risk for childhood acute leukemia (p<0.05). Conclusion: Results of this study indicate that childhood acute leukemia may be associated with breast-feeding, economic status, and number of children. Further cohort studies on factors causing acute Leukemia in children are recommended. |
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| Keywords: Breast-feeding, Related factors, Acute leukemia, Case-control study |
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Full-Text [PDF 263 kb]
(3726 Downloads)
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Type of Study: Original |
Subject:
General
Received: 2010/08/10 | Accepted: 2011/12/14 | Published: 2012/05/15
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