[Home ] [Archive]   [ فارسی ]  
:: Main :: About :: Current Issue :: Archive :: Search :: Contact ::
Main Menu
Home::
Journal Information::
Articles archive::
For Authors::
For Reviewers::
Subscription::
Contact us::
Site Facilities::
::
Search in website

Advanced Search
Receive site information
Enter your Email in the following box to receive the site news and information.
Last site contents
:: Editorial Board
:: About Iranian Journal of Endocrinology and Metabolism
:: Volume 9, Issue 1 (Junne 2007 2007) ::
2007, 9(1): 29-35 Back to browse issues page
Alanin aminotransferase activity in veterans exposed to sulfur mustard
M Ghanei , SM Alavian , M Nassiri , SH Assari
, ghanei1341@yahoo.com
Abstract:   (25796 Views)
Introduction: Until now, few studies have focused on late effect of sulfur mustard on the liver at present there is no data published on liver enzymes in sulfur mustard exposed veterans. The current study was conducted with the aim of determining alanine aminotransferase (ALT) levels in veterans exposed to sulfur mustard. Materials and Methods: In this cross-sectional study, 263 sulfur mustard exposed veterans were selected from among individuals referring to the respiratory clinic in Bagiyatallah hospital in 2005. ALT was determined in all subjects. Demographic data, exposure related variables, respiratory status and Body Mass Index (BMI) were collected. ALT over 40 unit/liter was considered as abnormal. Results: From a total of 263 sulfur mustard exposed veterans, 43 (16.3%) patients had an elevated ALT level. Range of ALT was 3-94 with a mean (SD) of 26.43 ± 15.22 unit/liter. ALT was correlated with the BMI (r=0.153, p=0.013). ALT was not significantly correlated with age, grading of chemical and overall disability. Mean ALT levels in patients with BMI > 25 (28.81 ± 15.05) were significantly higher than those with BMI less than 25 (21.93 ± 14.58) (p=0.001). Mean ALT level was higher in those with FEV1/FVC, in comparison to others (p<0.05). ALT was not significantly correlated with other study variables (p>0.05). Conclusion: Although any conclusion of the impact of mustard gas on ALT needs a controlled study, we mean while suggest serial measurement of the activity of this enzyme and other measures of liver status.
Keywords: Chemical warfare exposed veteran- Mustard Gas- Liver- Liver enzyme- alanine aminotransferase
Full-Text [PDF 319 kb]   (2907 Downloads)    
Type of Study: Original | Subject: Endocrinology
Received: 2007/08/20 | Published: 2007/07/15
Add your comments about this article
Your username or Email:

CAPTCHA


XML   Persian Abstract   Print


Download citation:
BibTeX | RIS | EndNote | Medlars | ProCite | Reference Manager | RefWorks
Send citation to:

Ghanei M, Alavian S, Nassiri M, Assari S. Alanin aminotransferase activity in veterans exposed to sulfur mustard. Iranian Journal of Endocrinology and Metabolism 2007; 9 (1) :29-35
URL: http://ijem.sbmu.ac.ir/article-1-373-en.html


Rights and permissions
Creative Commons License This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.
Volume 9, Issue 1 (Junne 2007 2007) Back to browse issues page
مجله ی غدد درون‌ریز و متابولیسم ایران، دو ماهنامه  پژوهشی مرکز تحقیقات غدد درون‌ریز و متابولیسم، Iranian Journal of Endocrinology and Metabolism
Persian site map - English site map - Created in 0.06 seconds with 38 queries by YEKTAWEB 4652