Association between Polycystic Ovary Morphology and Serum Prolactin Level
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H Bayat , S Nazarpour , M Mousavi , F Ramezani Tehrani |
Department of Midwifery, Faculty of Medical Sciences, Varamin-Pishva Branch, Islamic Azad University, Tehran, Iran. , snazarpour@gmail.com |
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Abstract: (131 Views) |
Introduction: Polycystic ovary morphology (PCOM) is an ultrasound finding and, according to the Rotterdam criteria, one of the diagnostic criteria for polycystic ovary syndrome (PCOS) in adult women. Given the hormonal changes, such as serum prolactin levels, associated with the number of ovarian follicles and ovulation, this study aimed to investigate the relationship between PCOM (based on ultrasound evidence) and different serum prolactin levels. Materials and Methods: In this study, data from the PCOS prevalence study in Iran and the PCOS prevalence study in Khuzestan were used. In these studies, a multi-stage cluster random sampling method was employed for sample selection, and data collection involved completing a questionnaire, conducting face-to-face interviews, collecting fasting venous blood samples for laboratory evaluations, and performing ovarian ultrasounds. In the present study, based on the inclusion criteria, 750 women were enrolled in two groups: the PCOM group (120 individuals) and the control group (630 individuals). A quantile regression model was used to assess the relationship between PCOM and prolactin levels, with a significance level set at p<0.05. Results: The mean prolactin levels did not significantly differ between the PCOM group and the control group. Even after adjusting for potential confounding factors (such as age, body mass index, and number of pregnancies), the quantile regression model revealed no significant differences in prolactin levels across any quintile between women with PCOM and the control group (p>0.05). Conclusion: Our population-based study showed that prolactin levels are not significantly different between the healthy group and those affected by PCOM. |
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Keywords: Polycystic Ovaries, Prolactin, Polycystic ovary morphology |
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Full-Text [PDF 762 kb]
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Type of Study: Original |
Subject:
Endocrinology Received: 2024/04/7 | Accepted: 2024/07/29 | Published: 2023/12/31
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