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:: Volume 15, Issue 4 (12-2013) ::
2013, 15(4): 333-339 Back to browse issues page
Effect of Ardeh on Components of Metabolic Syndrome in Type 2 Diabetic Patients: A Randomized Clinical Trial
Mahdieh Golzarand, Zahra Bahadoran, Somayeh Hosseinpour-Niazi, Sahar Mirzaee, Fereidoun Azizi, Parvin Mirmiran
Department of Clinical Nutrition and Dietetics, Faculty of Nutrition Sciences and Food Technology, National Nutrition and Food Technology Research Institute, Shahid Beheshti University of Medical Sciences , mirmiran@endocrine.ac.ir
Abstract:   (21606 Views)

Introduction: Metabolic syndrome is a cluster of metabolic disorders associated with cardiovascular disease. Animal and human experimental studies have shown the beneficial effects of sesame oil on the components of the metabolic syndrome however, the effect of Ardeh (grounded sesame seed) is unclear. The aim of this study was to determine effect of Ardeh on components of the metabolic syndrome in type 2 diabetic patients. Materials and Methods: In this clinical trial, 40 type 2 diabetic patients were recruited and randomly assigned into two groups, the control and Ardeh consumers. The breakfast energy content of participants, was planned at around 270 kcal. In the Ardeh consumer group, part of their breakfast was replaced by 2 Tsp Ardeh, whereas controls consumed the usual breakfast. Waist circumference, systolic and diastolic blood pressure, serum concentrations of glucose, triglycerides and HDL-C were measured at baseline and again 6 weeks after intervention. Results: In the Ardeh consumer group after six weeks mean serum triglyceride concentration decreased significantly (144±9.8 vs. 175±11.4 mg/dL) (P<0.05) and HDL-C increased (51.7±1.7 vs. 11.5 mg/dL), compared with controls. Means of other components of metabolic syndrome showed no significant changes between Ardeh consumer and control groups. Conclusions: Our results suggest that consumption of 28 g/d Ardeh has a beneficial effect on some components of metabolic syndrome, findings that need to be confirmed by further investigations.

Keywords: Ardeh, Sesame, Metabolic syndrome, Triglyceride, Glucose, HDL-C
Full-Text [PDF 282 kb]   (3884 Downloads)    
Type of Study: Original | Subject: Nutrition
Received: 2012/12/30 | Accepted: 2013/04/16 | Published: 2013/12/15
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Golzarand M, Bahadoran Z, Hosseinpour-Niazi S, Mirzaee S, Azizi F, Mirmiran P. Effect of Ardeh on Components of Metabolic Syndrome in Type 2 Diabetic Patients: A Randomized Clinical Trial. Iranian Journal of Endocrinology and Metabolism. 2013; 15 (4) :333-339
URL: http://ijem.sbmu.ac.ir/article-1-1486-en.html

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Volume 15, Issue 4 (12-2013) Back to browse issues page
مجله ی غدد درون‌ریز و متابولیسم ایران، دو ماهنامه  پژوهشی مرکز تحقیقات غدد درون‌ریز و متابولیسم، Iranian Journal of Endocrinology and Metabolism
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