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Introduction: In traditional medicine turnip (Brassica napus), is used to reduce blood glucose. Furthermore, Turnip also has antioxidant effects and many plants with antioxidant activities are known to have antidiabetic properties. Therefore in this study, the antihyperglycemic effect of boiled turnip extract and metabolic changes on triglycerides, cholesterol, high density lipoprotein (HDL) and low density lipoprotein (LDL) in diabetic rats were investigated. Materials and Methods: In this experimental study, 40 male Wistar rats, weighing 200 to 250g were divided in to 4 groups: control, diabetic control, diabetic group receiving cooked Turnip and diabetic group receiving Glibenclamide. Diabetes was induced by injection of 120 mg/kg alloxan monohydrate on 3 consecutive days. Rats in the third group received 16ml/kg turnip extract daily for 4 weeks after which the animals were anesthetized and blood samples were taken to measure the factors mentoned. Data were analyzed by Analysis of Variance test using SPSS software. Results: Boiled turnip extract significantly reduced serum glucose, triglycerides, cholesterol and LDL, and increase HDL, in diabetic rats compared to the control diabetic group (p<0.05). Conclusion: This study demonstrated that boiled turnip extract can reduce blood glucose and lipid levels in diabetic rats and may be used as complementary or alternative treatment for diabetic patients.

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Introduction: Diabetes is a metabolic disease characterised by chronic hyperglycemia. Considering the properties antioxidant of the Chevil plant compounds, this study performed to determine the effect of hydroalcoholic extract of Chevil on serum glucose and lipid in diabetic male rats. Materials and Methods: In this study, 54 male Wistar rats weighing 200-250 g were divided into 6 groups (n=9 each) and studied for 4 weeks. The groups were as follows: Control, diabetic, diabetic groups treated 200, 400 and 800 mg/kg body weight of the Chevil extract, respectively and the diabetic rats treated with 150 mg/kg body weight of metformin. At the end of study, FBS, Cholesterol, Triglycerides, HDL-C, and LDL-C levels were measured. Results were analyzed by one-way ANOVA. Results: Findings showed a significant reduction (P<0.05) of FBS in all groups with three doses of the extract, 26%, 59.3%, 69.4% respectively), Triglycerides (at 200 and 400 mg/kg of the extract respectively 16.1% and 34.1%), Cholesterol (800 mg/kg of the extract, 20.9%), LDL-C in all three doses of the extract, 25.9%, 49.1% and 53% respectively and a significant increase (P<0.05) in HDL-C in all three doses of the extract, 32.6%, 36.4% and 37.1% respectively compared to the control group was observed in diabetic rats treated with Chevil. Conclusion: The results of this study showed that Chevil extract reduces blood sugar and improves blood lipid profiles in diabetic rats.