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:: Volume 13, Issue 3 (9-2011) ::
2011, 13(3): 309-314 Back to browse issues page
Effect of 8 Weeks Endurance Training With Two Different Durations on Plasma HDL-Ghrelin in Male Rats
Abbas Ghanbari-Niaki Dr, Rozita Fathi Dr, Soghra Ramroudi, Mehdi Hedayati Dr
, hedayati@endocrine.ac.ir
Abstract:   (35598 Views)

Introduction: Ghrelin, produced and secreted mainly from the stomach, is a potent stimulator of growth hormone, appetite, and plays a role in energy balance control. There is increased risk of metabolic syndrome with increased LDL-C and TC levels and decreased HDL-C, with lower ghrelin concentrations. The purpose of this study was to compare the effect of different 8-week endurance training regimens on HDL-Ghrelin. Materials and Methods: Thirty Wistar male rats, 6-8 weeks of age, were randomly assigned to 3 groups of 10 rats, including two training groups with either 30 or 90 min of exercise, and a control group. Experimental groups were trained for 8 weeks, 5 days per week at 20m/min for 30 or 90 min. Rats were sacrificed 72 h after the last training session and plasma samples were collected for determining HDL-Ghrelin, HDL-C, HDL-2, HDL3, TG and TC. Analysis was performed using ANOVA and LSD post-hoc test, SPSS 16, at the alpha level of 0.05. Results: Ghrelin concentration paralleled HDL-Ghrelin changes. There was no difference in HDL-Ghrelin between groups. Despite reduction of TC in the training groups, no significant relationship was observed between HDL-Ghrelin and HDL2, HDL3, TG and TC. Conclusion: This study showed that isolated HDL contained Ghrelin. In addition, the 8 weeks endurance training of different durations had no correlation with HDL-Ghrelin and lipid profiles. Further studies to confirm these findings are warranted.

Keywords: HDL-Ghrelin, HDL2, HDL3, Endurance training, Training duration bread, Barley bread, Dislipidemia, Lipid profile
Full-Text [PDF 269 kb]   (1915 Downloads)    
Type of Study: Original | Subject: Exercise
Received: 2010/01/14 | Published: 2011/09/15
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Ghanbari-Niaki A, Fathi R, Ramroudi S, Hedayati M. Effect of 8 Weeks Endurance Training With Two Different Durations on Plasma HDL-Ghrelin in Male Rats. Iranian Journal of Endocrinology and Metabolism. 2011; 13 (3) :309-314
URL: http://ijem.sbmu.ac.ir/article-1-872-en.html

Volume 13, Issue 3 (9-2011) Back to browse issues page
مجله ی غدد درون‌ریز و متابولیسم ایران، دو ماهنامه  پژوهشی مرکز تحقیقات غدد درون‌ریز و متابولیسم، Iranian Journal of Endocrinology and Metabolism
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