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:: Volume 11, Issue 1 (5-2009) ::
2009, 11(1): 41-47 Back to browse issues page
Long-term Effects of Processed Berberis Vulgaris on Some Metabolic Syndrome Components
Ebrahimi-Mamaghani, Arefhosseini, Golzarand , Aliasgarzadeh, Vahed-Jabbary
, mahdieh_golzarand@yahoo.com
Abstract:   (40144 Views)


Introduction: Metabolic syndrome is complex of metabolic disorders that correlates with cardiovascular disease. This study aimed at investigating the effect of processed Berberis vulgaris (B.vulgaris) on some metabolic syndrome components. Materials and Methods: Participants, type2 diabetics, were recruited in a randomized controlled clinical trial (n = 57) and randomly assigned into three groups: 1) processed B.vulgaris (n =19), 2) apple vinegar group (n =19) and 3) control group (n =19). Height, weight, serum total cholesterol, HDL-, LDL-cholesterol, triglycerides, glucose and insulin concentrations were measured at baseline and at the end of the 8th week and BMI, total/HDL-cholesterol ratio and insulin resistance were estimated. Results: Processed B.vulgaris group showed no significant effects on BMI, total cholesterol, triglycerides and glucose concentrations, whereas LDL-cholesterol concentration (22.48±35.44mg/dl) and total/HDL-cholesterol ratio (2.56±4.87) significantly decreased and HDL-cholesterol concentration (12.33±20.58mg/dl) increased (P<0.05). No significant effect on lipid profiles was found in the apple vinegar group. Increased insulin concentration and insulin resistance was observed in all of these groups (P<0.001), independent of processed B.vulgaris and apple vinegar effects. Conclusion: Findings of the present study showed the beneficial effects of processed B.vulgaris on certain atherosclerosis risk factors.


Keywords: Berberis vulgaris, Apple vinegar, LDL-C, HDL-C, Triglycerides, Glucose, Insulin
Full-Text [PDF 288 kb]   (5325 Downloads)    
Type of Study: Original |
Received: 2009/06/10 | Published: 2009/05/15
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Ebrahimi-Mamaghani, Arefhosseini, Golzarand, Aliasgarzadeh, Vahed-Jabbary. Long-term Effects of Processed Berberis Vulgaris on Some Metabolic Syndrome Components. Iranian Journal of Endocrinology and Metabolism. 2009; 11 (1) :41-47
URL: http://ijem.sbmu.ac.ir/article-1-709-en.html

Volume 11, Issue 1 (5-2009) Back to browse issues page
مجله ی غدد درون‌ریز و متابولیسم ایران، دو ماهنامه  پژوهشی مرکز تحقیقات غدد درون‌ریز و متابولیسم، Iranian Journal of Endocrinology and Metabolism
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