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:: Volume 9, Issue 2 (IJEM Vol 9, No. 2 2007) ::
2007, 9(2): 205-212 Back to browse issues page
Variation of Urinary Iodine Concentration Within a Month During the First Trimester of Pregnancy in Tehran an Iodine-Repleted Area and Comparison to Non-Pregnant Women
A. Amozgar PhD , A. Ordokhani PhD, F. Azizi PhD
, atiehamouzegar@yahoo.com
Abstract:   (19954 Views)
Introduction: In order to assess variations of urinary iodine concentration (UIC) during a 4-week period among pregnant and non-pregnant women in an iodine-replete area. Materials and Methods: Pregnant and non-pregnant women referred to two maternity hospitals in Tehran were consecutively recruited from September 2005 to March 2006 urine samples (5–10 mL) were collected on an every-other-day basis for 4 weeks (i.e., 12 samples for each individual). UIC was determined using modified Sandell-Kolthoff method. Results: Thirty-six pregnant and 32 non-pregnant women completed the study. Mean±SD age of pregnant women was 27.4±6.4 and that of non-pregnant women was 27.6±4.5 years (p=0.897). Mean±SD gestational age was 11.0±3.3 weeks in pregnant participants. Median UIC of <100, 100-149, 150-249, and ≥250 µg/L was present in 19.4, 25.0, 30.6, and 25.0% of pregnant, 15.6, 37.5, 34.4, and 12.5% of non-pregnant, and 17.6, 30.9, 32.4, and 19.1% of total individuals, respectively. Median UIC values of sample, numbers 1 to 12 were not significantly different either in pregnant (p=0.591) or in non-pregnant subjects (p=0.745), except for sample number 11, median UIC was not significantly different between pregnant versus non-pregnant women (P values > 0.05). Mean SD value for UIC in samples number 1 to 12 in pregnant women was 138.4 (24.1–404), whereas in non-pregnant women this value was118.0 (29.5-272.4) µg/L (p=0.286). Conclusion: There was a wide intrapersonal variation in UIC values among pregnant and non-pregnant women residing in an iodine-replete area, supporting the notion that casual UIC would not reflect iodine status of the individual.
Keywords: Urinary Iodine, Pregnancy
Full-Text [PDF 327 kb]   (2642 Downloads)    
Type of Study: Original | Subject: Endocrinology
Received: 2007/10/20
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Amozgar A, Ordokhani A, Azizi F. Variation of Urinary Iodine Concentration Within a Month During the First Trimester of Pregnancy in Tehran an Iodine-Repleted Area and Comparison to Non-Pregnant Women. Iranian Journal of Endocrinology and Metabolism. 2007; 9 (2) :205-212
URL: http://ijem.sbmu.ac.ir/article-1-406-en.html


Volume 9, Issue 2 (IJEM Vol 9, No. 2 2007) Back to browse issues page
مجله ی غدد درون‌ریز و متابولیسم ایران، دو ماهنامه  پژوهشی مرکز تحقیقات غدد درون‌ریز و متابولیسم، Iranian Journal of Endocrinology and Metabolism
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