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:: Volume 19, Issue 4 (12-2017) ::
2017, 19(4): 234-243 Back to browse issues page
The Effect of Aqueous Extract Thymus kotschyanus Boiss. et Hohen on Glycemic Control and Dyslipidemia Associated with Type II Diabetes: a Randomized Controlled Trial
AM Taleb Dr, F Qannadi Dr, S Changizi-Ashtiyani Dr , A Zarei Dr, MR Rezvanfar, A Akbari Dr, D Hekmatpou Dr
, ashtiyani@yahoo.com
Abstract:   (1839 Views)

Introduction: The prevalence of diabetes mellitus, a major cause of death and disability, is increasing worldwide. Considering the data available on folk medicine in Iran, this study aimed to investigate hypoglycemic and hypolipidemic effects of the aqueous extract of the plant, Thymus kotschyanus Boiss. et Hohen (Thymus. K) in patients with type II diabetes. Materials and Methods: This study is a clinical trial in which 64 patients, aged 30-60 years, with confirmed diagnosis of Type II diabetes treated with usual anti-diabetic drugs normally were randomly divided into two groups, 1. (receiving usual drugs) and 2. (Receiving Thymus. K aqueous extracts 20 gr/day with conventional therapy). Three months later, indicators of glycemic control and lipid profiles were reassessed in both groups and compared with baseline values respectively. Results: Results showed that the groups receiving the aqueous extract Thymus. K (20 gr/day for three months) in addition to usual drugs, showed a significant decrease (p<0.05) in FBG and Hb A1C levels and a significant increase (p<0.05) in the beta cell function index (HOMA-Beta) while significantly reducing (p<0.05) is LDL-C levels. Conclusion: The aqueous extract of the plant Thymus. K in patients with type II diabetes along with the usual anti-diabetic drugs, led to better control glucose levels and also helped lower of LDL-C levels.

Keywords: Diabetes type 2, Thymus kotschyanus, dyslipidemia
Full-Text [PDF 450 kb]   (384 Downloads)    
Type of Study: Original | Subject: Endocrinology
Received: 2017/04/3 | Accepted: 2017/08/7 | Published: 2017/12/9
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Taleb A, Qannadi F, Changizi-Ashtiyani S, Zarei A, Rezvanfar M, Akbari A et al . The Effect of Aqueous Extract Thymus kotschyanus Boiss. et Hohen on Glycemic Control and Dyslipidemia Associated with Type II Diabetes: a Randomized Controlled Trial. Iranian Journal of Endocrinology and Metabolism. 2017; 19 (4) :234-243
URL: http://ijem.sbmu.ac.ir/article-1-2225-en.html


Volume 19, Issue 4 (12-2017) Back to browse issues page
مجله ی غدد درون‌ریز و متابولیسم ایران، دو ماهنامه  پژوهشی مرکز تحقیقات غدد درون‌ریز و متابولیسم، Iranian Journal of Endocrinology and Metabolism
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