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:: Volume 15, Issue 3 (10-2013) ::
2013, 15(3): 303-310 Back to browse issues page
A Simpler Diagnostic Method to Assess Hirsutism in the Iranian Population: Based on Modified Ferriman- Gallwey Scoring System (Tehran Lipid and Glucose Study)
Fahimeh Ramezani Tehrani Dr , Sonia Minooee , Masumeh Simbar Dr, Fereidun Azizi Dr
Reproductive Endocrinology Research Centre, Research Institute for Endocrine Sciences , ramezani@endocrine.ac.ir
Abstract:   (5560 Views)

Introduction: Hirsutism is a common endocrine disorder among reproductive women. There is no clear definition and criterion for the clinical evaluation and diagnosis of hirsutism. The aim of present study is to introduce a simpler diagnostic method on the basis of modified Ferriman- Gallwey (mF-G) system, which examines fewer body areas, but with the same sensitivity, spec­ificity and positive predictive value (PPV). Materials and Methods: A one thousand women, aged 18-45 years, participants of the Tehran Lipid and Glucose Study, were recruited by random systematic sampling. Data were collected by a questionnaire and clinical examination. The total mF-G score was calculated and ROC curve was drawn for subsets of areas. The new cut-off points were calculated for those subsets with optimal sensitivity, specificity, positive and negative predictive value and concordance percentage. Results: The subset of 5 areas of the lips, chin, thighs, upper and lower abdomen (cut-off point 5), had sensitivity and specificity of 97/5% and 89/9% (R²= 0/92%, P<0.0001) respectively, and was the nearest subset to mF-G method. The subset of lip, abdomen and thighs (cut- off point 4) was 91/5% sensitive and 92% specific, with the highest PPV (72/2%) and concordance percentage (91/9%) with the golden standard (mF-G score ≥ 8). Conclusion: Using the 3 area subset of lip+ lower abdomen+ thighs serves as a simple and more accepted method for hirsutism assessment and can be used in wide epidemiologic studies.

 

Keywords: Hirsutism, modified Ferriman- Gallwey scoring system, Community based study, Iranian women
Full-Text [PDF 444 kb]   (1722 Downloads)    
Type of Study: Original | Subject: Gynecology
Received: 2013/01/29 | Accepted: 2013/09/28 | Published: 2013/09/28
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Ramezani Tehrani F, Minooee S, Simbar M, Azizi F. A Simpler Diagnostic Method to Assess Hirsutism in the Iranian Population: Based on Modified Ferriman- Gallwey Scoring System (Tehran Lipid and Glucose Study). Iranian Journal of Endocrinology and Metabolism. 2013; 15 (3) :303-310
URL: http://ijem.sbmu.ac.ir/article-1-1507-en.html


Volume 15, Issue 3 (10-2013) Back to browse issues page
مجله ی غدد درون‌ریز و متابولیسم ایران، دو ماهنامه  پژوهشی مرکز تحقیقات غدد درون‌ریز و متابولیسم، Iranian Journal of Endocrinology and Metabolism
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