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:: Volume 14, Issue 5 (1-2013) ::
2013, 14(5): 445-454 Back to browse issues page
Effect of L-carnitine Supplementation with or Without Moderate Aerobic Training on Serum Lipid Profile and Body Fat Percentage in Obese Women
Mina Karimi , Maryam Rafraf Dr , Mohammadreza Rashidi Prof, Afshar Jafari Dr
Nutritional Research Center, Faculty of Health & Nutrition, Tabriz University of Medical Sciences , rafrafm@tbzmed.ac.ir
Abstract:   (8231 Views)

Introduction: Obesity, a serious risk factor for chronic diseases, especially among women, is an important worldwide public health problem. The aim of this study was to evaluate the effects of L-carnitine supplementation with or without moderate aerobic training on serum lipid profiles and body fat percentage in obese women. Materials and Methods: In this clinical trial, 44 obese women were randomly assigned to 4 groups (n=11 each) as follows: 1: L-carnitine supplementation (2 g/day), 2: aerobic training+placebo group, 3: L-carnitine supplementation + aerobic training and 4: placebo. All interventions had an 8 week period and subjects of aerobic training groups underwent 8-week aerobic training protocol (3 sessions a week [24 sessions]). Body mass index, body fat percentage, daily dietary intake and serum fasting free L-carnitine, total cholesterol, triglycerides, LDL and HDL cholesterol levels of each subjects were measured before and after interventions. Analysis of covariance was used for comparing of variables means between groups. Results: Body fat percentage decreased significantly in the aerobic training+placebo and in L-carnitine supplementation+aerobic training groups. In the L-carnitine supplementation group, aerobic training+pl­acebo and the L-carnitine supplementation+aerobic training groups, significant reductions were observed in serum total cholesterol and triglyceride levels. LDL-C levels decreased significantly in the L-carnitine+aerobic training group. Conclusion: Results indicated beneficial effects of L-carnitine supplementation alone or combined with aerobic training on serum lipid profiles and effects of aerobic training in lowering of body fat percentage in obese women. L-carnitine supplementation and aerobic training may be effective in delaying onset of chronic diseases in obese subjects.

Keywords: Obesity, L-carnitine, Aerobic training, Lipid profile, Body fat percentage
Full-Text [PDF 333 kb]   (1876 Downloads)    
Type of Study: Original | Subject: Nutrition
Received: 2012/04/15 | Accepted: 2012/06/30 | Published: 2014/05/24
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Karimi M, Rafraf M, Rashidi M, Jafari A. Effect of L-carnitine Supplementation with or Without Moderate Aerobic Training on Serum Lipid Profile and Body Fat Percentage in Obese Women. Iranian Journal of Endocrinology and Metabolism. 2013; 14 (5) :445-454
URL: http://ijem.sbmu.ac.ir/article-1-1368-en.html


Volume 14, Issue 5 (1-2013) Back to browse issues page
مجله ی غدد درون‌ریز و متابولیسم ایران، دو ماهنامه  پژوهشی مرکز تحقیقات غدد درون‌ریز و متابولیسم، Iranian Journal of Endocrinology and Metabolism
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