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:: Volume 14, Issue 2 (7-2012) ::
2012, 14(2): 150-155 Back to browse issues page
Is Subcutaneous Fat Tissue Associated with Coronary Artery Disease?
Masoumeh Sadeghi, Zahra Pourmoghaddas , Ali Hekmatnia, Hamid Sanei, Nizal Sarrafzadegan
Assistant Researcher, Cardiac Rehabilitation Research Center, Isfahan Cardiovascular research Institute, Isfahan University of Medical Sciences, Isfahan, Iran , zahrapormoghadas@yahoo.com
Abstract:   (9699 Views)

Introduction and aim: To evaluate the association of superficial, deep and total subcutaneous fat with coronary artery disease. Materials and Methods: This is a cross-sectional study, conducted on 122 patients with stable angina pectoris (SA). Fasting blood samples were taken to measure levels of fasting blood sugar (FBS), total cholesterol (TC), low- and high-density lipoprotein cholesterol (LDL-C, HDL-C), and triglycerides (TG). Systolic and diastolic blood pressure were measured for all patients, and coronary angiography was performed to detect coronary artery involvements based on angiography results, participants were divided to patients with (n=73) and without coronary artery disease (n=50). Three days later patients underwent abdominal computerized scan (CT) to determine superficial, deep and total subcutaneous fat. To evaluate the possible correlation between superficial, deep and total subcutaneous fat and coronary artery disease, pearson correlation test was used initially and then linear regression test was used for adjusting age and sex as well as history of hypertension, diabetes mellitus and dyslepidemia. Results: Of one hundred and twenty-two patients, mean age of 52.5±7.6 y, 73 patients had coronary artery involvements superficial (β=1, P=0.94) and deep (β=1, P=0.91). After adjusting for age and sex as well as history of hypertension, diabetes mellitus and dyslepidemia, no significant association was found between CAD and subcutaneous fat tissue. Conclusion: No association was found between different kinds of subcutaneous fat and coronary artery disease.

Keywords: Coronary artery disease, Adipose tissue, Subcutaneous fat
Full-Text [PDF 260 kb]   (2554 Downloads)    
Type of Study: Original | Subject: Cardiology
Received: 2011/05/29 | Accepted: 2012/01/10
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sadeghi M, pourmoghaddas Z, hekmatnia A, Sanei H, Sarrafzadegan N. Is Subcutaneous Fat Tissue Associated with Coronary Artery Disease?. Iranian Journal of Endocrinology and Metabolism. 2012; 14 (2) :150-155
URL: http://ijem.sbmu.ac.ir/article-1-1157-en.html


Volume 14, Issue 2 (7-2012) Back to browse issues page
مجله ی غدد درون‌ریز و متابولیسم ایران، دو ماهنامه  پژوهشی مرکز تحقیقات غدد درون‌ریز و متابولیسم، Iranian Journal of Endocrinology and Metabolism
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