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:: Volume 13, Issue 5 (1-2012) ::
2012, 13(5): 459-466 Back to browse issues page
Prevalence of Gastrointestinal Symptoms in Type 2 Diabetic Patients and its Association with Glycemic Control and Duration of Diabetes
Hajie bibi Shahbazian, Sayed Jalal Hashemi, Maryam Arghideh , Farshid Fardad, Sayed Mahmood Latifi
Ahvaz diabetes research center , drarghidehm@yahoo.com
Abstract:   (20240 Views)

Abstract

Introduction: Long-standing uncontrolled type 2 DM may affect the motility and function of the gastrointestinal (GI) system, throughout the GI tract, from the esophagus to the anorectal region. This study was designed to evaluate the prevalence of GI symptoms in type 2 DM patients and its association to age, sex, glycemic control and duration of diabetes. Materials and Methods: This was a cross-sectional study conducted on 350 adult type 2 DM patients, selected with sequential sampling from the Ahvaz Diabetes Research Center Clinic in 2010. Data were collected by a questionnaires and analyzed using independent t-test and Chi-score with SPSS version18. Results: Patient mean age was 56 ± 11 years, and the prevalence of GI symptoms was 67%. The most prevalent GI symptoms were constipation (43%), bloating (35%) and regurgitation (31%). Prevalence of GI symptoms was related to duration of diabetes (P<0.001). Higher levels of fasting plasma glucose increased the prevalence of GI symptoms (P=0.003), which were significantly higher in females than in males (P<0.001), and also in older patients (P=0.003). There was no association between prevalence of GI symptoms and levels of HbA1C or BMI. Conclusion: Prevalence of GI symptoms in type 2 DM was 67%, the most prevalent being constipation, bloating and regurgitation. There was significant association between prevalence of GI symptoms and acute glycemic control (FBS), duration of type 2 diabetes, female gender and age.

 

Keywords: Type 2 diabetes mellitus, GI symptoms, Glycemic control, HbA1C
Full-Text [PDF 287 kb]   (1644 Downloads)    
Type of Study: Original | Subject: Endocrinology
Received: 2011/05/15 | Accepted: 2011/09/7
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Shahbazian H B, Hashemi S J, Arghideh M, Fardad F, Latifi S M. Prevalence of Gastrointestinal Symptoms in Type 2 Diabetic Patients and its Association with Glycemic Control and Duration of Diabetes. Iranian Journal of Endocrinology and Metabolism. 2012; 13 (5) :459-466
URL: http://ijem.sbmu.ac.ir/article-1-1150-en.html


Volume 13, Issue 5 (1-2012) Back to browse issues page
مجله ی غدد درون‌ریز و متابولیسم ایران، دو ماهنامه  پژوهشی مرکز تحقیقات غدد درون‌ریز و متابولیسم، Iranian Journal of Endocrinology and Metabolism
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