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Association between Mediterranean Diet and DASH Diet and the Risk of Cardiovascular Disease: A Cohort from Tehran Lipid and Glucose Study
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M Golzarand    , Z Bahadoran , P Mirmiran , F Azizi |
| Nutrition and Endocrine Research Center, Research Institute for Endocrine Disorders, Research Institute for Endocrine Sciences, Shahid Beheshti University of Medical Sciences, Tehran, Iran, , mahdieh_golzarand@yahoo.com |
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Abstract: (32 Views) |
Introduction: Previous studies have demonstrated the beneficial effects of the Mediterranean diet (MeDi) and the Dietary Approaches to Stop Hypertension (DASH) diet for preventing cardiovascular disease (CVD). However, only a few cohort studies have investigated the association between adherence to the MeDi and DASH dietary patterns and the risk of CVD in Iranians. Therefore, this study was designed to determine the association between adherence to the MeDi and DASH diet scores and CVD risk among Iranian adults. Materials and Methods: In this cohort study, 3055 adults from the Tehran Lipid and Glucose Study (TLGS) were selected. A food frequency questionnaire was used to assess participants' dietary intake and to determine the MeDi and DASH diet scores. The association between the MeDi and DASH diet scores and the risk of CVD was assessed using Cox proportional hazards regression model. Results: The mean age of participants was 39.3 years, and 55.2% were women. During a 10-year follow-up, 202 cases of CVD were identified. After adjusting for potential confounders, the HR (95% CI) for CVD incidence was 0.85 (0.77-0.94) and 0.94 (0.91-0.97) for each unit increase in the MeDi and DASH scores. The results of the restricted cubic spline analysis indicated that the observed associations were nonlinear. In dose-response analyses, the HR for CVD in the highest tertile of the MeDi score was 0.52 (0.37-0.74), and for the highest tertile of the DASH score, it was 0.48 (0.32-0.72), compared with those in the lowest tertile of the scores. Conclusion: The findings suggest that the Mediterranean diet and the DASH diet are appropriate dietary patterns for the prevention of cardiovascular disease among the Iranian population. |
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| Keywords: Mediterranean diet, DASH diet, Cardiovascular disease, Dietary pattern |
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Full-Text [PDF 866 kb]
(44 Downloads)
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Type of Study: Original |
Subject:
Nutrition
Received: 2025/12/21 | Accepted: 2026/04/11 | Published: 2026/04/30
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