fa ارتباط روی سرم با استرس اکسیداتیو، غلظت انسولین و مقاومت به انسولین در زنان یائسه‌ی مبتلا به دیابت نوع 2 پژوهشی Original <p class="Abstract" style="MARGIN: 0cm 1cm 0pt DIRECTION: ltr unicode-bidi: embed TEXT-ALIGN: justify"><font face="Arial"><strong>Abstract</strong></font></p><p class="Abstract" style="MARGIN: 0cm 1cm 0pt DIRECTION: ltr unicode-bidi: embed TEXT-ALIGN: justify"><strong><font face="Arial"><u>Introduction</u>: The metabolism of Zine (Zn), an essential nutrient, changes in diabetes. It has been shown that there is a relationship between Zn and both, type 1 or insulin-dependent diabetes mellitus (IDDM) and type 2 or non-insulin-dependent diabetes mellitus (NIDDM). Increased lipid peroxidation in diabetic patients leads to MDA production. This study aimed to investigate relationships between serum Zn concentration and insulin, insulin resistance and oxidative stress in postmenopausal diabetic women. <u>Materials and Methods</u>: We studied 45 diabetic women and 45 healthy ones (controls) with BMI 25-30 kg/m2 and age 45-60 y. Fasting blood sugar (FBS), serum zinc, insulin, insulin resistance and MDA were determined in both groups. <u>Results</u>: There were non significant correlations between Zn, insulin<span dir="rtl"></span></font><span dir="rtl" style="FONT-SIZE: 11pt FONT-FAMILY: Lotus mso-ansi-font-size: 9.0pt"><span dir="rtl"></span> </span><span dir="ltr"></span><span dir="ltr"></span><font face="Arial">(r= -0.06) and insulin resistance (r = -0.027) and MDA<span dir="rtl"></span></font><span dir="rtl" style="FONT-SIZE: 11pt FONT-FAMILY: Lotus mso-ansi-font-size: 9.0pt"><span dir="rtl"></span> </span><span dir="ltr"></span><span dir="ltr"></span><font face="Arial">(r = -0.09) as well in diabetic group. <u>Conclusion</u>: There were no significant relationships between serum zinc and insulin, insulin resistance and MDA in postmenopausal diabetic women.</font></strong></p> روی، استرس اکسیداتیو، انسولین، دیابت نوع 2 Type 2 diabetes mellitus, Zinc , Oxidative stress, Insulin 485 489 http://ijem.sbmu.ac.ir/browse.php?a_code=A-10-81-78&slc_lang=fa&sid=1 M Taghdir مریم تقدیر 4000319475328460011353 4000319475328460011353 No M Jalali محمود جلالی jalalikh@sina.tums.ac.ir 4000319475328460011426 4000319475328460011426 Yes A Djazayeri سید ابوالقاسم جزایری 4000319475328460011427 4000319475328460011427 No M Ashourpour مهکامه عاشورپور 4000319475328460011428 4000319475328460011428 No A Rajab اسدا... رجب 4000319475328460011429 4000319475328460011429 No انجمن دیابت ایران، تهران M Sepandi مجتبی سپندی 4000319475328460011430 4000319475328460011430 No M Zareei مهناز زارعی 4000319475328460011431 4000319475328460011431 No