fa ارتباط بین مدت زمان شیردهی با ابتلا به لوسمی حاد در کودکان پژوهشی Original <p class="Abstract" style="MARGIN: 0cm 1cm 0pt DIRECTION: ltr unicode-bidi: embed TEXT-ALIGN: justify"><strong><font face="Arial">Abstract</font></strong></p><p class="Abstract" style="MARGIN: 0cm 1cm 0pt DIRECTION: ltr unicode-bidi: embed TEXT-ALIGN: justify"><strong><font face="Arial"><u>Introduction</u>: The role of breast-feeding in protection against childhood acute leukemia is uncertain. In this study, we tested the hypothesis that breast-feeding decreases the risk of 300 patients we investigated childhood acute leukemia. <u>Materials and Methods</u>: In a case control study, we inrestigated 300 patients, aged 2±13 years, with acute leukemia, as well as 300 controls, individually matched for age and sex. Information regarding breast-feeding was obtained through face to face interviews with mothers. <u>Results</u>: Findings showed that there was a significant relationship between duration of breast-feeding and childhood acute leukemia (P<0. 001). Breast-feeding of less than 1-months durations, when compared with feeding of longer durations 19-24 months was associated with increased risk of childhood acute leukemia (OR=3. 54). <u>Conclusion:</u> In this study, breast-feeding was associated with a reduced risk of childhood acute leukemia. Our findings suggest that future epidemiologic and experimental efforts should be directed at investigating the relationship between breast-feeding duration and all malignancies among children. </font></strong></p> Breast-feeding; Acute leukemia, Case-control study 185 190 http://ijem.sbmu.ac.ir/browse.php?a_code=A-10-4-75&slc_lang=fa&sid=1 S Nikpour صغری نیک پور s-nikpour@iums.ac.ir 400031947532846006258 400031947532846006258 Yes Sh Rahimian شیما رحیمیان 400031947532846006259 400031947532846006259 No Sh Shokrabi شعله شکرابی 400031947532846006260 400031947532846006260 No H Haghani حمید حقانی 400031947532846006261 400031947532846006261 No