fa بررسی میزان ذخایر آهن سرم در زنان بدون اضافه وزن مبتلا به سندرم تخمدان پلی‌کیستیک و رابطه‌ی آن با مقاومت به انسولین پژوهشی Original <p class="Abstract" style="MARGIN: 0cm 1cm 0pt DIRECTION: ltr unicode-bidi: embed TEXT-ALIGN: justify"><strong><font face="Arial">Abstract</font></strong></p><p class="Abstract" style="MARGIN: 0cm 1cm 0pt DIRECTION: ltr unicode-bidi: embed TEXT-ALIGN: justify"><strong><font face="Arial"><u>Introduction</u>: Polycystic ovarian syndrome (PCOS) is the most common cause of anovulation and hyperandrogenism, and obesity and insulin resistance are usually associated with this disease. Body iron stores are positively associated with glucose intolerance, type 2 diabetes mellitus, gestational diabetes and metabolic syndrome. It is reported that serum ferritin levels increase in obese women with PCOS. The aim of this study was to evaluate this relationship in women, neither overweight or obese, but suffering from PCOS. <u>Materials and Methods</u>: Fifty women with PCOS, without overweight, were selected based on the <city w:st="on"><place w:st="on">Rotterdam</place></city> workshop criteria. After 12 hours fasting, serum ferritin, fasting blood sugar, cholesterol, triglycerides, HDL and insulin were measured and insulin resistance was calculated by HOMA-IR data was compared with that of 38 asymptomatic control subjects, matched for BMI and age. <u>Results</u>: In the patient group, mean age was 27±5.78 years and mean BMI was 21.11±3.82 Kg/m² mean serum ferritin in patients was 60.45±32.39, being 47.48±23.65 ng/mL in controls. Insulin resistance in patients was 2.61±0.91 and 1.74±0.72 in controls. Increases in serum ferritin, insulin and insulin resistance in patients were not statistically significant. There was no correlation between body iron stores and serum insulin level, insulin resistance and serum lipoproteins. <u>Conclusion</u>: Results showed that in non-overweight women with PCOS there is no significant increment of body iron stores.</font></strong></p> سندرم تخمدان پلی‌کیستیک، فریتین سرم، مقاومت به انسولین، زنان فاقد اضافه وزن Polycystic Ovarian Syndrome, Ferritin, Insulin resistance, Non overweight women 599 603 http://ijem.sbmu.ac.ir/browse.php?a_code=A-10-4-45&slc_lang=fa&sid=1 M. Taghavi مرتضی تقوی mortezataghavi2003@yahoo.com 400031947532846005011 400031947532846005011 Yes S. Fatemi صدیقه فاطمی 400031947532846005012 400031947532846005012 No H. Ayatollahi حسین آیت الهی 400031947532846005013 400031947532846005013 No