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Tehran Lipid and Glucose Study (TLGS): rationale and design
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| F Azizi , M Madjid, M Rahmani, H Emami, P Mirmiran, R Hadjipour |
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Abstract: (63711 Views) |
| Abstract: Tehran Lipid and Glucose Study is a study to determine the risk factors for atherosclerosis among Tehran urban population and develop population-based measures to change the lifestyle of the population and prevent incidence of diabetes mellitus and dyslipidemia. 17000 men and women between 3 and 69 years of age are randomly sampled from Tehran urban district 13 for assessment of conventional (i.e. smoking, diabetes and hypertension) and emerging (i.e. glucose intolerance, obesity, physical activity and diet) cardiovascular risk factors. In the baseline examination a general questionnaire on persons’ health condition and risk factors is filled up and a brief physical examination is done. Cardiovascular disease is assessed by using a 12-lead electrocardiogram and London School of Hygiene Cardiovascular (Rose) Questionnaire. The relationship between the conventional and emerging risk factors and vascular disease and markers of end-organ damage will be evaluated in the urban residents of Tehran. In the second phase of the study, healthy individuals will be followed up in a 10-year-long cohort to determine the trend of changes in lipid and glucose status and development of vascular complications. Selected people undergo interventions with modifications in their lifestyle to assess the efficacy of certain measures in preventing the development of diabetes mellitus and dyslipidemia. |
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| Keywords: Population-based study, Lipid disorders, Diabetes mellitus, Cardiovascular risk factors |
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Full-Text [PDF 275 kb]
(6801 Downloads)
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Type of Study: Original |
Subject:
Endocrinology
Received: 2006/11/14 | Published: 2000/06/15
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