[Home ] [Archive]   [ فارسی ]  
:: Main :: About :: Current Issue :: Archive :: Search :: Contact ::
Main Menu
Journal Information::
Articles archive::
For Authors::
For Reviewers::
Contact us::
Site Facilities::
Search in website

Advanced Search
Receive site information
Enter your Email in the following box to receive the site news and information.
Last site contents
:: Editorial Board
:: About Iranian Journal of Endocrinology and Metabolism
:: Volume 10, Issue 6 (3-2009) ::
2009, 10(6): 639-646 Back to browse issues page
Effects of Estrogen and progesterone On Endometrial Glycocalyx Expression In Superovulated Mice in The Implantation Window Time
B. Niknafs , F. Afshari
, niknafsbeh@yahoo.com
Abstract:   (18535 Views)


Introduction: It has been reported that apical glycocalyx expression of uterine affects embryo implantation. The aim of this study was to determine endometrial glycocalyx and endometrial thickness after estrogen and progesterone injection in hyperstimulated mice at luteal phase. Materials & Methods: Adult male and female mice were used for induction of pesudopregnancy. The mice were divided into two groups experimental and control groups. Female mice in the experimental group were superovulated and were then mated with vasectomised mice to induce psudopregnancy Experimental group based on hormone injection was subdivided into five groups 1) Estrogen, 2) Progesterone, 3) Estrogen + Progesterone, 4) Antiprogesterone + Estrogen, 5) Sham. Pesudopregnancy in the control group was achieved without any hyperstimulation. The uterines of all groups were collected after 4.5 days of pregnancy and prepared for the assessment of endometrial thickness and endometrial glycocalyx expression. Results: The results showed that estrogen and progesterone injection increased the intensity of PAS reaction, whereas progesterone decreased this. Also our results showed that the endometrial thickness in the sham group was the highest and in the progesterone group was the lowest. Conclusion: Our results showed that addition of estrogen to progesterone, compared to P supplementation alone, provided appropriate endometrial conditions to embryo implantation. Hence combination of estrogen and progesterone injection as luteal support hormones can be used in IVF protocols.
Keywords: Implantation, Ovarian hyperstimulation, Glycocalyx, Endometrium
Type of Study: Original |
Received: 2009/04/19 | Published: 2009/03/15
Add your comments about this article
Your username or Email:


XML   Persian Abstract   Print

Download citation:
BibTeX | RIS | EndNote | Medlars | ProCite | Reference Manager | RefWorks
Send citation to:

Niknafs B, Afshari F. Effects of Estrogen and progesterone On Endometrial Glycocalyx Expression In Superovulated Mice in The Implantation Window Time. Iranian Journal of Endocrinology and Metabolism 2009; 10 (6) :639-646
URL: http://ijem.sbmu.ac.ir/article-1-675-en.html

Rights and permissions
Creative Commons License This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.
Volume 10, Issue 6 (3-2009) Back to browse issues page
مجله ی غدد درون‌ریز و متابولیسم ایران، دو ماهنامه  پژوهشی مرکز تحقیقات غدد درون‌ریز و متابولیسم، Iranian Journal of Endocrinology and Metabolism
Persian site map - English site map - Created in 0.05 seconds with 37 queries by YEKTAWEB 4624