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:: Volume 17, Issue 4 (12-2015) ::
2015, 17(4): 308-315 Back to browse issues page
Comparison of Aerobic Exercise and Caloric Restriction on Serum Preptin Levels and Indicators of Insulin Resistance in Obese Sedentary Women
Azam Ramezankhani , Rahman Soori, Ali asghar Ravasi, Ali Akbarnejad
tehran university , ramezankhanizm@gmail.com
Abstract:   (7890 Views)

Introduction: Preptin is a recently isolated peptide hormone that is co-secreted with insulin from the pancreatic beta-cells. The aim of this study was to compare the effects of aerobic exercise and caloric restriction on serum preptin levels and HOMA-IR in sedentary obese women. Materials and methods: Forty women who referred to home health centers were divided into four groups for 16 weeks of follow up: Aerobic exercise (experimental group 1), caloric restriction (experimental group 2), aerobic exercise with caloric restriction (experimental group 3) and the control group. Training programs in experimental group 1 consisted of aerobic training and running on a treadmill for 105.183±5.63 minutes, 4 times a wk. In experimental group 2, subjects followed a diet with caloric restriction equivalent to physical activity energy expenditure. Subjects in the experimental group 3 used a training program similar to experimental group 1 for 66.85±5.34 minutes, 3 times a wk and received a diet with half the amount of caloric restriction of experimental group 2. Results: Weight, BMI and WHR showed significant reduction in the experimental groups. Serum preptin levels were decreased by 21.97%, 28.32% and 27.11% in experimental groups 1, 2 and 3 respectively. HOMA-IR was decreased significantly in the 3 groups. Significant correlations were seen between changes of preptin and changes of weight, WHR and HOMA-IR (p<0.05). Conclusion: Considering the relationship between preptin and insulin resistance and the influence of aerobic exercise and caloric restriction, preptin may play an effective role in weight management and prevention of diabetes.

Keywords: Preptin, Insulin resistance, Aerobic exercise, Caloric restriction, Obese sedentary women
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Type of Study: Original | Subject: Exercise
Received: 2015/07/3 | Accepted: 2015/09/13 | Published: 2015/12/15
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ramezankhani A, soori R, ravasi A A, akbarnejad A. Comparison of Aerobic Exercise and Caloric Restriction on Serum Preptin Levels and Indicators of Insulin Resistance in Obese Sedentary Women. Iranian Journal of Endocrinology and Metabolism. 2015; 17 (4) :308-315
URL: http://ijem.sbmu.ac.ir/article-1-1962-en.html

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Volume 17, Issue 4 (12-2015) Back to browse issues page
مجله ی غدد درون‌ریز و متابولیسم ایران، دو ماهنامه  پژوهشی مرکز تحقیقات غدد درون‌ریز و متابولیسم، Iranian Journal of Endocrinology and Metabolism
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