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Cut-off point identification for quantitative ultrasonography in comparison to dual X-ray absorptiometry to diagnose osteoporotic menopausal women
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B Larijani   , H Dabagh Manesh , M Sedaghat , M Akrami , Z Hamidi , E Rahimi |
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Abstract: (28573 Views) |
| Introduction: Dual X ray absorptiometry (DXA) is the preferred method for bone mineral density (BMD) studies. Quantitative ultrasonography (QUS), however, has advantages in that it is less expensive, portable and does not expose the individual to radiation. These advantages have suggested a role for QUS in screening studies. In this study, we tried to determine cutoff values for this method. Materials and Methods: 420 menopausal women were recruited. BMD values were determined with both QUS and DXA methods. T scores were calculated and the relation between the two T-scores measured in each participants were assessed. The agreement between the two T-scores calculated by the QUS and DXA was assessed by Kappa test in lumbar and femoral neck regions. Results: Kappa scores as measure of agreement between T-scores measured by QUS and DXA, were 0.31 for lumbar region and 0.5 for femoral neck region. Score -1 was determined as the cutoff point for calcaneus bone QUS studies. Conclusions: Determination of a cutoff point for QUS, obviates performing unnecessary DXA and provide the opportunity for large scale studies. |
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| Keywords: Osteoporosis, Menopause, BMD, QUS, DXA |
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Full-Text [PDF 306 kb]
(2758 Downloads)
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Type of Study: Original |
Subject:
Endocrinology
Received: 2006/11/20 | Published: 2004/03/15
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