Introduction: Considering the importance of obesity and lifestyle behaviors, especially physical activity. The aim of this study was to investigate the association of obesity, overweight and some demographic factors with physical activity in adults of Rasht city. Materials and Methods: Two hundred men (mean ± SD: 40.27 ± 13.6 years) and 200 women (mean ± SD: 40.41 ± 12.3 years) participated in this study. Anthropometric data including weight, height, waist and hip circumferences, and body mass index (BMI) were obtained using standard methods. Physical activity level was measured by International Physical Activity Questionnaire (IPAQ). Results: Of subjects, 13.5, 43 and 43.5% had low, medium and high, social / economic conditions, respectively. The lowest percentage of subjects were labourers (1.5%) and the highest (37.5%) were self-employed. Prevalence of overweight, obesity and central obesity were 52%, 23.5% and 47.75%, respectively (men 54%, 14.5% and 25.5% women 50%, 32.5% and 56%). The prevalence of obesity increased with age (P<0.05). The obese subjects had lowest levels of physical activity. Physical activity levels including walking, moderate and high activity were 59.5, 22.5 and 11.5% and 66.5, 14, 7% among men and women, respectively. The others did not perform any physical activity. Physical activity had an inverse relationship with overweight, obesity and central obesity (P<0.05). Conclusions: Low level of physical activity is one of the causes of obesity and overweigt, indicating that level of physical activity in men and women is highly recommended for these individuals.