:: Volume 23, Issue 4 (11-2021) ::
2021, 23(4): 233-239 Back to browse issues page
The Effect of Eight Weeks of High-intensity Interval Training on Serum Levels of VCAM-1 and E-selectin in Women with Polycystic Ovary Syndrome
F Shahidi , AA Gaeini , M Afghan , R Hosseini
Department of Sport Physiology Faculty of Sport Science, Shahid Rajayee Teacher Training University, Tehran, Iran, , Fe-shahidi@sru.ac.ir
Abstract:   (1128 Views)
Introduction: Women with polycystic ovary syndrome (PCOS) are at increased risk of developing cardiovascular diseases. Exercise is a therapeutic strategy to improve vascular function and reduce patient mortality. Thus, this study aimed to evaluate the effect of eight weeks of high-intensity interval training (HIIT) on serum levels of VCAM-1 and E-selectins in women with PCOS. Materials and Methods: Thirty females with PCOS aged between 18 and 40 years were randomly categorized into an HIIT group and a control group. The HIIT program was administered three sessions a week for eight weeks. Serum levels of VCAM-1 and E-selectins were measured before and after the intervention after an overnight fast of 10 h. The data were analyzed using SPSS software (version 23). Results: After the intervention, a significant difference was observed in serum E-selectin levels in the HIIT group (p=0.037) compared to the control group (P>0.05). However, no significant changes were observed in serum VCAM-1 levels in the HIIT group after the intervention (P≥0.05). Conclusion: The findings demonstrated that eight weeks of HIIT could improve endothelial function in women with PCOS.
Keywords: PCOS, HIIT, Endothelial function, E-selectin, VCAM-1
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Type of Study: Original | Subject: Exercise
Received: 2022/03/25 | Accepted: 2022/05/28 | Published: 2021/11/1

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Volume 23, Issue 4 (11-2021) Back to browse issues page