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Comparison of sperm quality and sex hormones levels before and after renal transplantion
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GH Pourmand   , R Zohrehvand , M Alavi , A Esteghamati , R Mehrsay , M Taheri |
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Abstract: (32203 Views) |
| Abstract: To evaluate sex hormones profile and sperm quality in hemodialysed and live-related renal transplant patients the plasma levels of sex hormones (FSH, LH, Testoserone, Prolactin) and spermogram in 30 men [mean 38 years (24-52)] who were under hemodialysis for at least 6 months were studies. The same sex hormones and spermogram were determined at six months interval. Control group were 30 healthy men with mean age of 37 years (22-52). Mean prolactin was 16.6ng/ml (3.5-40) (P=0.001), mean FSH 9.6mIU/ml (2.5-20) (P=0.001), mean LH 8.6mIU/ml (2.2-16.5) (P=0.004) in hemodialized patients, while mean testosterone level mean 3.92 (95% CI= 1-9) (P=0.02) was lower in hemodialized patients. In hemodialized group the sperm normal morphology was observed in 55.31% (95% CI= 30-80) (P= 0.002), mean sperm motility was 50.62% (95% CI = 32-70) (P= 0.001) and sperm count was 60.62 mil/ml (95% CI= 40-75) (P= 0.05). The mean prolactin 10.52 ng/ml (95% CI= 2-25) (P= 0.001), mean FSH 7.04nlU/ml (95% CI= 2-12) (P= 0.01) and mean LH 8.75 nlU/ml (95% CI= 1.5-16.5) (P= 0.001) decreased and mean testosterone level 4.5ng/ml (95% CI= 1.7-8.5) (P= 0.005) increased significantly 6 months after transplantation. Sperm motility mean (56.56%) (95% CI= 50-75) (P= 0.006) was saignificantly improved while other paterns showed moderate improvement. Sex hormone disturbance and spermogram abnormality are common consequences of chronic renal failure. Renal transplantation restores most of these hormone abnormalities, sperm quality and sexual dysfunctiona. |
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| Keywords: Sex hormones, Spermogram, Renal Transplantation, Hemodialysis |
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Type of Study: Original |
Subject:
Endocrinology
Received: 2006/11/30 | Published: 2000/12/15
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