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:: Volume 20, Issue 6 (3-2019) ::
2019, 20(6): 295-302 Back to browse issues page
Relationship between Basal Metabolic Rate and Serum Parathyroid Hormone and Body Composition in Women with Secondary Hyperparathyroidism
Mahdieh Abbasalizad-Farhangi Dr , Alireza Ostadrahimi Dr
Tabriz University of Medical Sciences , abbasalizad_m@yahoo.com
Abstract:   (699 Views)

Introduction: Several factors including fat free mass and fat mass can affect Basal Metabolic Rate (BMR) as the largest component of daily energy demand. The aim of the current cross-sectional study was to compare BMR in women with secondary hyperparathyroidism and healthy women and to evaluate its relationship with serum Parathyroid Hormone (PTH), fat free mass and fat mass in these subjects. Materials and Methods: Sixty-eight women, 34 with secondary by hyperparathyroidism and 34 healthy controls, aged between 17-50 years, participated in the current study. Serum PTH, 25 hydroxy vitamin D and alkaline phosphatase were measured by the Enzyme linked immunoassay technique (ELISA), Chemiluminescence Immunoassays (CLIA) and enzymatic methods respectively. Serum calcium, phosphorous and magnesium were measured calorimetrically. BMR, fat mass and fat free mass were analyzed by the Bioelectrical Impedance Analyzer (BIA). Results: Mean BMR and fat free mass of women with secondary hyperparathyroidism, was significantly lower than those of healthy ones (P<0.02). Serum PTH concentration in women with secondary hyperparathyroidism was significantly higher and serum phosphorous, significantly lower than healthy women (P<0.05). There was a significant negative relationship between BMR and serum PTH in all participants. Fat mass and fat free mass were also significantly correlated with BMR in both groups (P<0.05). Conclusion: According to our results, there is a negative relationship between BMR and serum PTH in all study participants. Further studies with interventional designs for inference of the causality of associations are warranted.

Keywords: Basal Metabolic Rate, Secondary Hyperparathyroidism, Fat free mass, Fat Mass
Full-Text [PDF 529 kb]   (161 Downloads)    
Type of Study: Original | Subject: Endocrinology
Received: 2017/11/1 | Accepted: 2019/03/12 | Published: 2019/04/22
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Abbasalizad-Farhangi M, Ostadrahimi A. Relationship between Basal Metabolic Rate and Serum Parathyroid Hormone and Body Composition in Women with Secondary Hyperparathyroidism. Iranian Journal of Endocrinology and Metabolism. 2019; 20 (6) :295-302
URL: http://ijem.sbmu.ac.ir/article-1-2338-en.html


Volume 20, Issue 6 (3-2019) Back to browse issues page
مجله ی غدد درون‌ریز و متابولیسم ایران، دو ماهنامه  پژوهشی مرکز تحقیقات غدد درون‌ریز و متابولیسم، Iranian Journal of Endocrinology and Metabolism
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