Introduction: The study compared the effectiveness of three methods of green tea extract consumption, aerobics and a combination of these two methods, on the chemerin level and insulin resistance in obese women. Materials and Methods: This semi-experimental study was conducted in 1391 in Isfahan on 36 females aged 33.63±4.78 years with BMI 33.80±4.11 kg/m², selected and grouped randomly into four groups the aerobic exercise, green tea extract, combined (green tea extract along with aerobic exercise) and the control group. The aerobic training program included three sessions per week for 12 weeks the green tea extract group consumed 500mg green tea extract capsule for 12 weeks, three times a day after meals, and the third group underwent a combination of aerobic exercise and consumption of green tea extract. Body composition, glucose, insulin and chemerin level were measured in all four groups before and after intervention. Insulin resistance index (HOMA-IR) was calculated by the relevant equation. Analysis of variance (ANOVA) was used for between group comparisons (significance level P<0.05). Result: Results showed that after 12 weeks, in the exercise group no significant differences in weight, BMI, fat percent, WHR, serum levels of chemerin, insulin, glucose and insulin resistance index (P>0.05). Conclusion: All three methods reduced body composition, although not significantly. Increasing the exercise intensity or duration could lead to more desirable results. Regarding other exercise variables there was no significant change between groups, but these results need to be interpreted cautiously as the motivation and diets of participants were not controlled.