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The Correlation between Plasma ICAM-1 Levels and Cardiorespiratory Fitness and Anthropometric Indexes in Middle Age Subjects
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Maryam Nourshahi   , Saleh Zahedi asl , Mona Sehhat |
| Shahid Beheshti University , m-nourshahi@sbu.ac.ir |
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Abstract: (8778 Views) |
| Introduction: Inter cellular adhesion molecule -1 (ICAM-1) is an important new factor which can predict cardiovascular disease (CVD). Accordingly, the purpose of this study was to investigate the correlation between plasma concentrations of inter cellular adhesion molecule–1 (ICAM-1) and cardiorespiratory fitness and anthropometric indices as noninvasive methods. Materials and Methods: From all among the male and female university personnel, 127 (72 men and 55 women) healthy and nonsmoker subjects (age: 36.62±5.7 years, VO2max:27.32±6.72 ml/kg.min) were selected using a medical questionnaire. Anticubital veinblood samples were taken in fasting status at rest. VO2max was then evaluated on a treadmill with gas analyzer and measurement of anthropometric factors (BMI, WHR and PBF) were measured in all the subjects in the laboratory. Serum ICAM-1 were measured by ELISA method. In women, controlling for their menstrual cycle, blood sampling was taken in follicular phase (3-8 days after onset of their menstrual period) and VO2max test was performed in 3-9 days (i.e., in the luteal phase). Data were analyzed using the Pearson correlation and multinomial regression. Results: The results showed that there were no significant correlations between ICAM-1 and VO2max, BMI, or PBF (P>0.05), wheares there was a signicant positive correlation between WHR and ICAM-1 in middle aged individuals (P=0.01). In addition, because of a strong correlation observed between VO2max and WHR (P=0.00), this factor could be used with WHR for more complete models in predicting the plasma concentration of ICAM-1. Conclusion: Findings showed that visceral fat tissue, compared to other factors, is more effective in predicting ICAM-1 concentrations. |
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| Keywords: Intercellular adhesion molecule – 1, BMI, VO2max, WHR, Body fat percent |
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Full-Text [PDF 323 kb]
(2474 Downloads)
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Type of Study: Original |
Subject:
Exercise
Received: 2012/03/11 | Accepted: 2013/03/6 | Published: 2013/03/6
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