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The prevalence of thyroid function disorders in CCU-admitted patients
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F Hajsheikholeslami   , MR Beyranvand , AS Moeini , M Sadeghi Ghahroudi , N Valaei |
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Abstract: (40354 Views) |
| Abstract: Thyroid function disorders (hypothyroidism and hyperthyroidism) are relatively common, and more frequently seen in females than in males. They have significant cardiovascular effects and often simulate cardiac diseases, specially hyperthyroidism that can induce and aggravate CAD, CHF and AF. Cardiac diseases and hyperthyroidism have some similar symptoms and signs, so clinical diagnosis of latter in the presence of the former is difficult. We evaluated 382 patients admitted to CCU of Modarres and Taleghani hospitals. After signing informed consent, TRH test was performed on all of them, clinical data including symptoms, signs, cardiac diagnosis and diagnostic methods, were evaluated too. Of these 382 patients, 186 (%48.7) were in Modarres and 196 (%51.3) in Taleghani hospital. Mean age of patients was 60.5±11.3 year. 164 (%42.9) were female and 218 (%57.7) male. History of thyroid disease was found in %10.7. %47.1 of patients had cardiac diagnosis of unstable angina, %17.8 AMI and %15.2 CHF. These ratios were similare in two hospitals. 27 (%6.3) of these 382 patients had thyroid function disorders including 9 (%2.4) hyperthyroidism and 15 (%3.9) hypothyroidism, of these 7 (%29.2) were female and 17 (%70.8) male, and only 3 (%13) had history of thyroid disease. 8 of 9 patients with hyperthyroidism were in Taleghani (%4.1 hyperthyroidism) and 1 in Modarres (%0.5 hyperthyroidism) (P<0.02) and all patient were male. 10 of 15 patients with hypothyroidism were in Taleghani (%5.1 hypothyroidism) and 5 (%2.7 hypothroidism) in Modarres hospital (P<0.35). 7 (%46.6) were female and 8 (%53.4) male. The prevalence of hypothyroidism in patients ≤50 year old (%9.6) was higher than that in patients 51-71 year old (%3.75) (P<0.07) but conversely the prevalence of hyperthyroidism in patients 51-71 year old (%4.2) was higher than in patient ≤ 50 year old (%0). 48 (%12.8) of all admitted patients had noncardiac disease and %10.4 of them had thyroid function disorders, %6.2 hypothyroidism and %4.2 hyperthyroidism. This research revealed that thyroid function disorders are relatively common in CCU-admitted patients and also more common in patients ≤ 50 year old. Hypothyroidism was more common than hyperthyroidism and hyperthyroidism more frequent in males than in females. |
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| Keywords: Hypothyroidism, Hyperthyroidism, Coronary care unit (CCU), Cardiovascular |
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Full-Text [PDF 350 kb]
(5518 Downloads)
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Type of Study: Original |
Subject:
Endocrinology
Received: 2006/11/15 | Published: 2000/09/15
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