Introduction: The aim of this study was to investigate the effects of lifestyle status on dyslipidemia which may be responsible for the metabolic syndrome. Materials and Methods: One hundred forty one males (n=47 mean ± SD: 43.7 ± 7.8 years of age) and females (n=94 mean ± SD: 43.7 ± 7.8 years of age) participated in this study. Each subject’s lifestyle status was assessed by self-administered questionnaires, based on Breslow’s lifestyle index and a composite dietary behavior score, obtained from self-reported responses to a 24-item food-frequency questionnaire, was used to categorize eating habits as more/less healthy. Results: The results demonstrated a negative relationship between Breslow’s lifestyle index and physical fitness level and dyslipidemia (P<0.05). On the other hand, the results showed that less healthy diets were associated with total cholesterol, triglycerides and LDL-C. Multiple regression analysis demonstrated that food consumption patterns were independently associated with blood lipid profiles in females, while physical fitness level was independently associated with blood lipid profiles in males. Conclusion: In conclusion, unhealthy lifestyles may cause dyslipidemia, findings which present reasonable explanations for the relationships between lifestyles and lifestyles-related diseases.